21 documents found, page 1 of 3
Corncob as carbon source in the production of xanthan gum in different strains ...
Jesus, Meirielly; Mata, Fernando; Batista, Rejane A.; Ruzene, Denise S.; Albuquerque-Júnior, Ricardo; Cardoso, Juliana C.; Vaz-Velho, ManuelaXanthan gum (XG) is a biopolymer obtained in fermentation and used as a rheology control agent in aqueous systems and in stabilizing emulsions and suspensions. XG, together with other polysaccharides, can form soft, cohesive composite gels. The carbon source in the fermentative process is responsible for one-third of the production costs, and the search for less expensive and sustainable alternatives is ongoing...
From oral formulations to drug-eluting implants: using 3D and 4D printing to de...
Willemen, Niels G. A.; Morsink, Margaretha A. J.; Veerman, Devin; da Silva, Classius F.; Cardoso, Juliana C.; Souto, Eliana Maria BarbosaSince the start of the Precision Medicine Initiative by the United States of America in 2015, interest in personalized medicine has grown extensively. In short, personalized medicine is a term that describes medical treatment that is tuned to the individual. One possible way to realize personalized medicine is 3D printing. When using materials that can be tuned upon stimulation, 4D printing is established. In r...
Photoprotection and skin irritation effect of hydrogels containing hydroalcohol...
Batista, Cinthia M.; Queiroz, Luma A. de; Alves, Ângela V. F.; Reis, Elisiane C. A.; Santos, Fagne A.; Castro, Tailaine N.; Lima, Bruno S.The use of natural products in sunscreen formulations as a prophylactic measure against skin cancer is receiving special attention attributed to the photoprotective and antioxidant properties of their chemical components. In this work, we describe the development of topical hydrogel formulations containing hydroalcoholic extract of red propolis (HERP), and the evaluation of the dermal sensitizing effect of the ...
Liposomal formulations of oxybutynin and resiniferatoxin for the treatment of u...
Cirino, Lorena M. D.; Vergne, Daviane M. C.; Novais, Gabrielle B.; Cano, Amanda; Padilha, Francine F.; Severino, PatríciaThe use of liposomes for drug release has demonstrated to be a promising therapeutic platform for biomedical applications. In this study, intravesical administration of OXI (1.5 mM) and RTX (100 nM) was used to compare histological changes caused in Wistar female rats by the drugs both unloaded and loaded in liposomes. After instillation of formulations by intravesical catheter, bladders were removed and histol...
Hydrogels for modified-release drug delivery systems
Zielinska, Aleksandra; Eder, Piotr; Rannier, Lucas; Cardoso, Juliana C.; Severino, Patrícia; Silva, Amélia M.; Souto, Eliana B.Hydrogels for the modified-release drug delivery systems is a continuously growing area of interest for the pharmaceutical industry. According to the global market, the use of polymers in this area is projected to reach $31.4 million by 2027. This review discusses the recent advances and perspectives of hydrogel in drug delivery systems for oral, parenteral, nasal, topical, and ophthalmic. The search strategy d...
Cymbopogon winterianus Essential Oil Attenuates Bleomycin-Induced Pulmonary Fib...
Tavares, Lívia A.; Rezende, Allan A.; Santos, Jymmys L.; Estevam, Charles S.; Silva, Ana M. O.; Schneider, Jaderson K.; Cunha, John L. S.The essential oil of Cymbopogon winterianus (EOCW) is a natural product with antioxidant, anti-inflammatory, and antifibrotic properties. We studied the effect of EOCW in the progression of histological changes of pulmonary fibrosis (PF) in a rodent model. The oil was obtained by hydrodistillation and characterized using gas chromatography-mass spectrometry. Intratracheal instillation of bleomycin was performed...
Cashew Gum (Anacardium occidentale) as a Potential Source for the Production of...
Loureiro, Kahynna C.; Jäger, Alessandro; Pavlova, Ewa; Lima-Verde, Isabel B.; Štěpánek, Petr; Sangenito, Leandro S.; Santos, André L. S.Every year, more than thirty thousand tons of Cashew gum (Anacardium occidentale, family: Anacardiaceae) are produced in Brazil; however, only a small amount is used for different applications in foodstuff and in pharmaceutical industries. As a raw material for the production of drug delivery systems, cashew gum is still regarded as an innovative compound worth to be exploited. In this work, cashew gum was extr...
Development of a Manometric Monitoring Method for Early Detection of Air Microb...
dos Santos-Neto, Agenor G.; Pinheiro, Malone S.; dos Santos, Monica C.; Alves, Lumar L.; Poderoso, Renata R. S.; Cardoso, Juliana C.; Severino, PatriciaAtmospheric air is a microbial habitat of pathogenic bioaerosols that may pose serious risks to humans. A commonly laboratory-based approach for the diagnosis of such infections in the bloodstream is the blood culture analysis. Its clinical relevance is attributed to the fact that these infections are characterized by high rates of morbidity and mortality, requiring the need for efficient methods for rapid diag...
Overcoming multi-resistant leishmania treatment by nanoencapsulation of potent ...
Oliveira, Simone S. C.; Ferreira, Carine S.; Branquinha, Marta H.; Santos, André L. S.; Chaud, Marco V.; Jain, Sona; Cardoso, Juliana C.Leishmaniasis corresponds to a group of neglected tropical diseases caused by flagellated protozoa belonging to the Leishmania genus. This widely spread illness is found in over 90 countries in the tropic and sub-tropic regions and also in southern Europe. As parasites exclusively infect the highly phagocytic cells (macrophages), this aspect can be exploited for targeted delivery making use of nanoparticles. Dr...
Cymbopogon winterianus essential oil attenuates bleomycin-induced pulmonary fib...
Tavares, Lívia A.; Rezende, Allan A.; Santos, Jymmys L.; Estevam, Charles S.; Silva, Ana M. O.; Schneider, Jaderson K.; Cunha, John L. S.The essential oil of Cymbopogon winterianus (EOCW) is a natural product with antioxidant, anti-inflammatory, and antifibrotic properties. We studied the effect of EOCW in the progression of histological changes of pulmonary fibrosis (PF) in a rodent model. The oil was obtained by hydrodistillation and characterized using gas chromatographymass spectrometry. Intratracheal instillation of bleomycin was performed ...