Made available in DSpace on 2021-06-25T10:58:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Objective: To assess the effects of epidermal growth factor (EGF)–coated titanium (Ti) discs on the adhesion and metabolism of keratinocytes and gingival fibroblasts exposed to nitrogen-containing bisphosphonates. Materials and methods: Keratinocytes and fibroblasts were seeded (1 × 105 cells/disc) on T...
Made available in DSpace on 2021-06-25T11:00:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-07-01; Objective: Oral mucositis (OM), the most common side effect of cancer therapy, is associated with pro-inflammatory cytokines and matrix metalloproteinases (MMPs) increased expression. Although there are approaches for OM management, none is infallible, thus, elucidation of molecular events related to OM...
Made available in DSpace on 2021-06-25T11:15:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-07-01; Objective: This study aimed to assess the influence of the bisphosphonates zoledronic acid and sodium alendronate on MMP-2 and MMP-9 synthesis and activity by gingival fibroblasts seeded onto titanium substrate. Design: Titanium discs were placed in 24-well cell culture plates and gingival fibroblasts w...
Made available in DSpace on 2020-12-12T01:55:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-07-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The aim of this study was to assess the effects of IL-6 and IL-8 cytokines on human gingival fibroblasts (HGF) cultured in a 3-D model and the possible photobiomodul...