Hereditary cerebellar ataxias (HCA) are a heterogeneous group of neurological disorders with several underlying genetic mechanisms. The available treatments are still scarce, however the growing interest in cerebellar neurostimulation has revealed promising results. We aimed to review the published studies on transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) in HCA. A li...
The Portugaliæ Monumenta Linguistica (PML) [Monuments of Portuguese Linguistics] platform presents a revolutionary tool for digital humanities, offering a unique corpus that includes Portu- guese Grammars, Orthographies, and monuments of Missionary Linguistics from the Portuguese Royal Patronage. Designed with user experience in mind, it provides a simplified and intuitive inter- face across various devices. Th...
Pathogenic biallelic variants in POGLUT1 were linked to limb-girdle muscular dystrophy R21 (LGMD R21), a new type of LGMD featuring pelvic and shoulder girdle weakness, variable age of onset, slowly progressive course, and “inside-to-outside” fatty degeneration pattern in muscle magnetic resonance imaging (MRI). We describe a 54-year-old female with an infantile-onset, slowly progressive, pelvicgirdle myopathy,...
No contexto de patrimônio cultural, identificou-se que a região possui um setor metalmecânico importante, no qual muitas empresas produzem para o setor automobilístico. Um selo é um importante instrumento para que os consumidores possam fazer suas escolhas, em diferentes segmentos, que via de regra, buscam informar características. Alguns selos são emitidos por Institutos como o INMETRO ou por outras entidades ...
Background: The amount of propofol needed to induce loss of responsiveness varied widely among patients, and they usually required less than the initial dose recommended by the drug package inserts. Identifying precisely the moment of loss of responsiveness will determine the amount of propofol each patient needs. Currently, methods to decide the exact moment of loss of responsiveness are based on subjective an...
The amount of propofol needed to induce loss of responsiveness varied widely among patients, and they usually required less than the initial dose recommended by the drug package inserts. Identifying precisely the moment of loss of responsiveness will determine the amount of propofol each patient needs. Currently, methods to decide the exact moment of loss of responsiveness are based on subjective analysis, and ...
General anesthesia is a reversible drug-induced state of altered arousal characterized by loss of responsiveness due to brainstem inactivation. Precise identification of the moment in which responsiveness is lost during the induction of general anesthesia is extremely important to provide information regarding an individual's anesthetic requirements and help intraoperative drug titration. To characterize the tr...
This work further clarifies how the MULTIS architecture can be used for integration of virtual worlds in learning management system (LMS) for organizational management of e-learning activities, as an extension to a previous work published in the proceedings of VEAI 2016. Current LMSs provide minimal support for educational use in an organizational context, and other integration efforts assume that educators are...
Learning Management Systems (LMS) provide minimal support for educational use of virtual worlds. Integration efforts assume the educators are inside the virtual world, providing hooks to services in the external LMS, to setup and manage virtual world activities. We present the inverse approach, enabling educators to setup and manage virtual world activities using the traditional LMS Web interface as an integral...
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Ambiental.; Neste trabalho foram realizados estudos com objetivo de determinar a produção de lodo na sedimentação para diversos coagulantes, mantendo-se a clarificação em níveis aceitáveis, na água do Rio Itajai Mirim, em reator estático. Para a execução deste trabalho foram usados os seg...