52 documents found, page 1 of 6

Frailty and nutritional status in institutionalized elderly patients with neuro...

Introduction: Frailty is a geriatric syndrome defined as a state of increased vulnerability to negative health outcomes that is considered the most powerful predictor of disability, dependence, institutionalization, and death, and so considered a major health burden. Malnutrition has been described to be independently associated with frailty. Objectives: The primary objective was to describe the frequency of fr...

Children’s literature in primary education: Creative writing practices

Desde cedo, é fundamental promover a construção da entidade leitora da criança, por meio de como se organizam os primeiros contactos da criança com o livro, possibilitando-lhe o desenvolvimento do pensamento crítico-reflexivo, da imaginação, da curiosidade e o seu sentido de descoberta. A par disso, a literatura é um veículo, que reúne um conjunto de condições, que nos possibilita ampliar o nosso olhar, por mei...

Teoria das Transições – Afaf Meleis

INTERCOMPARAÇÃO DE SIMULAÇÕES NUMÉRICAS COM MODELOS ATMOSFÉRICOS ACOPLADOS A MO...

A propagação do fogo associada à atividade piro-convectiva extrema é atualmente altamente imprevisível e difícil de combater. Este relatório apresenta os principais resultados de simulações realizadas a partir do acoplamento entre modelos de resolução de nuvens e modelos de propagação de fogo, nomeadamente MesoNH/ForeFire, WRF/FIRE e WRF/SFIRE. Os códigos acoplados foram utilizados no estudo dos mega incêndios ...

Relevance of Multigene Panels in the Molecular diagnosis of patients with disor...

Introduction: Next generation sequencing (NGS) is increasingly used in the molecular diagnosis of rare diseases, such as disorders of sexual development (DSD), allowing the analysis of a greater number of genes in a single assay, providing faster results with reduced costs. DSD patients may present high phenotypic overlap (genital ambiguity, sex reversal, delayed/absent puberty, infertility) posing challenges t...

COVID-19 Pandemic Impact on Metabolic Control of Type 1 Diabetes in Children

Introduction: Coronavirus disease 2019 pandemic has led to the adoption of extreme public health measures worldwide, and many governments imposed lockdown policies during the pandemic. In Portugal, the first emergency state began in March 2020 which led to the closure of schools and gyms, depriving children of all physical activities. This study aimed to evaluate the lockdown impact on metabolic control of chil...

Immunosensor for alpha-synuclein detection in Parkinson´s Disease

Parkinsons disease (PD) is a neurodegenerative disorder and one of the leading causes of death worldwide [1]. The principal neuropathological defining hallmark of PD is the presence of Lewy bodies mainly composed of aggregates of alpha-synuclein (-syn) [2]. This protein is a specific PD biomarker that, when detected early, can contribute to an effective PD treatment application. Immunosensors are analytical pla...

A Review on the Current Status of Numerical Weather Prediction in Portugal 2021...

Earth system modelling is currently playing an increasing role in weather forecasting and understanding climate change, however, the operation, deployment and development of numerical Earth system models are extremely demanding in terms of computational resources and human effort. Merging synergies has become a natural process by which national meteorological services assess and contribute to the development of...

Molecularly imprinted polymer-based electrochemical biosensor for alpha-synucle...

A novel and sensitive molecularly imprinted polymer (MIP)-based biosensor was developed for alpha synuclein synaptic neuronal protein detection, a specific Parkinson´s disease (PD) biomarker. PD is the second most common neurodegenerative disease worldwide [1]. The leading neuropathological defining hallmark of PD is the presence of Lewy bodies and Lewy neurites mainly composed of aggregates of alpha-synuclein ...

(Dys)Prosody in Parkinson’s disease: effects of medication and disease progress...

Abstract: The phonology of prosody has received little attention in studies of motor speech disorders. The present study investigates the phonology of intonation (nuclear contours) and speech chunking (prosodic phrasing) in Parkinson’s Disease (PD), as a function of medication intake and progression of the disease. Following methods of the prosodic and intonational phonology frameworks, we examined the ability ...