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Is the efflux pump inhibitor Verapamil a potential booster for isoniazid agains...
Ribeiro do Amaral, Renata Claro; Caleffi-Ferracioli, Katiany Rizzieri; Demitto, Fernanda de Oliveira; Almeida, Aryadne Larissa deMade available in DSpace on 2021-06-25T21:07:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; The membrane-based efflux pump systems are recognized to have an important role in pathogenicity and drug resistance in Mycobacterium tuberculosis by the extrusion of toxic substrates and drugs from the inner bacillus. This study aimed to investigate the in vitro interaction of Verapamil (VP), an efflux...
Is the efflux pump inhibitor Verapamil a potential booster for isoniazid agains...
Amaral, Renata Claro Ribeiro do; Caleffi-Ferracioli, Katiany Rizzieri; Demitto, Fernanda de Oliveira; Almeida, Aryadne Larissa deThe membrane-based efflux pump systems are recognized to have an important role in pathogenicity and drug resistance in Mycobacterium tuberculosis by the extrusion of toxic substrates and drugs from the inner bacillus. This study aimed to investigate the in vitro interaction of Verapamil (VP), an efflux pump inhibitor, with the classical first-line anti-tuberculosis drug isoniazid (INH) in resistant and suscept...
Molecular characterization of Mycobacterium tuberculosis and Mycobacterium bovi...
Caleffi-Ferracioli, Katiany Rizzieri; Baldin, Vanessa Pietrowski; Noguti, Erika Noda; Dias Siqueira, Vera Lucia; Lima Scodro, Regiane BertinMade available in DSpace on 2019-10-04T12:33:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-01-01. Added 1 bitstream(s) on 2021-07-15T15:22:59Z : No. of bitstreams: 1 S1984-82502018000300616.pdf: 1344399 bytes, checksum: d687808a7d6961d58527596b3b571c73 (MD5); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Tub...
A Nanostructures Lipid System to Improve the Oral Bioavailability of Ruthenium(...
Silva, Patricia B. da [UNESP]; Freitas, Eduardo Sinesio de [UNESP]; Solcia, Mariana Cristina [UNESP]; Souza, Paula Carolina de [UNESP]Made available in DSpace on 2019-10-05T04:10:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-06; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Post-Doctoral National Program (PNPD); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Tuberculosis (TB) is an infectious, airborne disease caused by the bacterium Mycobacterium tuberculosis that mainly affects the lungs...
Molecular characterization of Mycobacterium tuberculosis and Mycobacterium bovi...
Cardoso, Rosilene Fressatti
Anti-Mycobacterium tuberculosis activity of antituberculosis drugs and amoxicil...
Furlan Pagliotto, Aline Daniele; Caleffi-Ferracioli, Katiany Rizzieri; Lopes, Mariana Aparecida; Baldin, Vanessa PietrowskiMade available in DSpace on 2018-11-26T17:13:49Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-12-01; We report the in vitro drugs interaction by the resazurin drugs combination micro-titer assay (REDCA) of amoxicillin (AMO)/clavulanate (CLAV) with isoniazid (INH), ethambutol (EMB), and rifampicin (RIF) against susceptible and resistant Mycobacterium tuberculosis isolates. The addition of AMO/CLAV to cl...
Activity of rifampicin and linezolid combination in Mycobacterium tuberculosis
Maltempe, Flaviane Granero; Caleffi-Ferracioli, Katiany Rizzieri; Ribeiro do Amaral, Renata Claro; Demitto, Fernanda de OliveiraMade available in DSpace on 2018-11-26T17:31:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-05-01; Background: Linezolid (LZD) is not commonly used for treating tuberculosis (TB), but in some patients with drug-resistant TB it is being used. However, the in vitro LZD activity, in combination with rifampicin (RIF) against Mycobacterium tuberculosis has not been fully elucidated. Aims: The aim of this ...
Intramacrophage Mycobacterium tuberculosis efflux pump gene regulation after ri...
Canezin, Pedro Henrique; Caleffi-Ferracioli, Katiany Rizzieri; Lima Scodro, Regiane Bertin de; Dias Siqueira, Vera LuciaMade available in DSpace on 2018-11-29T21:58:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-07-01; Fundacao Araucaria; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Objectives: Since resistance of Mycobacteriumtuberculosis (Mtb) partially derives fromefflux pumps (EPs) in the plasma membrane, the current study evaluates EPs in Mtb exposed to rifampicin in the presence of the E...
Genotyping and rifampicin and isoniazid resistance in Mycobacterium bovis strai...
Franco, Marília Masello Junqueira [UNESP]; Ribeiro, Márcio Garcia [UNESP]; Pavan, Fernando Rogério [UNESP]; Miyata, Marcelo [UNESP]Made available in DSpace on 2018-12-11T17:10:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-05-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); In developing nations, 10–20% of the human cases of tuberculosis are caused by Mycobacterium bovis. However, this percentage may be underestimated because most laboratories in developing countries do not routinely perform mycobacterial cultu...
Prevalence of Streptococcus agalactiae colonization in pregnant women from the ...
Melo, Simone Cristina Castanho Sabaini de; Costa, Aline Balandis; Silva, Flávia Teixeira Ribeiro da; Silva, Natália Maria Maciel GuerraIntroduction The aim of this study was to determine the prevalence of GBS colonization in pregnant women in a public health service. Methods A study of 496 pregnant women at 35-37 gestational weeks was conducted from September 2011 to March 2014 in 21 municipalities of the 18th Health Region of Paraná State. Vaginal and anorectal samples of each woman were plated on sheep blood agar, and in HPTH and Todd-Hewitt...