Encontrados 4 documentos, a visualizar página 1 de 1
Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multic...
Pirnay, Jean-Paul; Djebara, Sarah; Steurs, Griet; Griselain, Johann; Cochez, Christel; De Soir, Steven; Glonti, Tea; Spiessens, An; Vanden Berghe, EmilyIn contrast to the many reports of successful real-world cases of personalized bacteriophage therapy (BT), randomized controlled trials of non-personalized bacteriophage products have not produced the expected results. Here we present the outcomes of a retrospective observational analysis of the first 100 consecutive cases of personalized BT of difficult-to-treat infections facilitated by a Belgian consortium i...
Isolation and characterization of the acadevirus members BigMira and MidiMira i...
da Silva, Jéssica Duarte; Bens, Lene; Santos, Adriele J. do Carmo; Lavigne, Rob; Soares, José; Melo, Luís Daniel Rodrigues; Vallino, MartaProteus mirabilis is an opportunistic pathogen and is responsible for more than 40% of all cases of catheter-associated urinary tract infections (CAUTIs). Healthcare-associated infections have been aggravated by the constant emergence of antibiotic-resistant bacterial strains. Because of this, the use of phages to combat bacterial infections gained renewed interest. In this study, we describe the biological and...
Characterization and Genomic Analysis of a New Phage Infecting Helicobacter pylori
Ferreira, Rute; Sousa, Cláudia; Gonçalves, Raquel F.S.; Pinheiro, Ana Cristina; Oleastro, Mónica; Wagemans, Jeroen; Lavigne, Rob; Figueiredo, CeuHelicobacter pylori, a significant human gastric pathogen, has been demonstrating increased antibiotic resistance, causing difficulties in infection treatment. It is therefore important to develop alternatives or complementary approaches to antibiotics to tackle H. pylori infections, and (bacterio) phages have proven to be effective antibacterial agents. In this work, prophage isolation was attempted using H. p...
Characterization and genomic analysis of a new phage infecting Helicobacter pylori
Ferreira, Rute Vanessa Novais; Sousa, Cláudia Sofia Cunha; Gonçalves, Raquel; Pinheiro, A. C.; Oleastro, Mónica; Wagemans, Jeroen; Lavigne, RobHelicobacter pylori, a significant human gastric pathogen, has been demonstrating increased antibiotic resistance, causing difficulties in infection treatment. It is therefore important to develop alternatives or complementary approaches to antibiotics to tackle H. pylori infections, and (bacterio)phages have proven to be effective antibacterial agents. In this work, prophage isolation was attempted using H. py...