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Real-world data from the Portuguese Nivolumab Expanded Access Program (EAP) in ...

Figueiredo, A; Almeida, M A; Almodovar, M T; Alves, P; Araújo, A; Araújo, D; Barata, F; Barradas, L; Barroso, A; Brito, U; Camacho, E; Canário, D

OBJECTIVE: The main aim of the study was to evaluate the efficacy and safety profile of Nivolumab, an immune-checkpoint-inhibitor antibody, in advanced, previously treated, Non-Small Cell Lung Cancer (NSCLC) patients, in a real world setting. METHODS: We performed a retrospective, multicentre data analysis of patients who were included in the Portuguese Nivolumab Expanded Access Program (EAP). Eligibility crite...

Date: 2020   |   Origin: Saúde - CUF

Anemia grave como apresentação de linfoma T Angioimunoblástico : um caso clínico

Almeida, MM; Barra, A; Gouveia, S; Magalhães, D; Teodoro, C; Fernandes, A; Cardoso, T; Ferreira, R; Mendes, D

Introdução: O linfoma T Angioimunoblástico é uma entidade rara, que representa 1 a 2% dos linfomas não Hodgkin, com envolvimento sistémico associado a fenómenos auto-imunes.1,2 Caracteriza-se por um comportamento agressivo e clinicamente por uma apresentação súbita de sintomas constitucionais, adenomegálias generalizadas, hepatoesplenomegália, anemia e hipergamaglobulinemia.2 Objetivos: Partilhar apresentação d...


Microbiology of healthcare-associated infections and the definition accuracy to...

Cardoso, T; Almeida, M; Carratalà, J; Aragão, I; Costa-Pereira, A; Sarmento, AE; Azevedo, L

BACKGROUND: Healthcare-associated infections (HCAI) represent up to 50 % of all infections among patients admitted from the community. The current review intends to provide a systematic review on the microbiological profile involved in HCAI, to compare it with community-acquired (CAI) and hospital-acquired infections (HAI) and to evaluate the definition accuracy to predict infection by potentially drug resistan...


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