2 documents found, page 1 of 1
Host immune genetic variations influence the risk of developing acute myeloid l...
Sánchez-Maldonado, J. M.; Campa, D.; Springer, J.; Badiola, J.; Niazi, Y.; Moñiz-Díez, A.; Hernández-Mohedo, F.; González-Sierra, P.; Ter Horst, R.The purpose of this study was to conduct a two-stage case control association study including 654 acute myeloid leukaemia (AML) patients and 3477 controls ascertained through the NuCLEAR consortium to evaluate the effect of 27 immune-related single nucleotide polymorphisms (SNPs) on AML risk. In a pooled analysis of cohort studies, we found that carriers of the IL13rs1295686A/A genotype had an increased risk of...
Polymorphisms in xenobiotic transporters ABCB1, ABCG2, ABCC2, ABCC1, ABCC3 and ...
Martino, A.; Campa, D.; Buda, G.; Sainz, J.; GarcIa Sanz, R.; Jamroziak, K.; Reis, R. M.; Weinhold, N.; Jurado, M.; Rıos, R.; Szemraj-Rogucka, ZofiaMultiple myeloma (MM) is a hematological neoplasm that arises from a single clone of malignant plasma cells in the bone marrow. In Europe, 4.6/100 000 males and 3.2/100 000 females every year develop MM, with a median age at diagnosis around 60 years.