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Decreased in situ expression of interleukin-10 receptor is correlated with the ...

Faria, Daniela Rodrigues de; Gollob, Kenneth John; Barbosa Júnior, José; Schriefer, Nicolaus Albert Borges; Machado, Paulo Roberto Lima; Lessa, Hélio

Human infection with Leishmania braziliensis can lead to cutaneous leishmaniasis (CL) or mucosal leishmaniasis (ML). We hypothesize that the intense tissue destruction observed in ML is a consequence of an uncontrolled exacerbated inflammatory immune response, with cytotoxic activity. For the first time, this work identifies the cellular sources of inflammatory and antiinflammatory cytokines, the expression of ...

Data: 2014   |   Origem: Oasisbr

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