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Mulberry biomass-derived nanomedicines mitigate colitis through improved inflam...

Yang, Wenjing; Ma, Ya; Xu, Haiting; Zhu, Zhenhua; Wu, Jiaxue; Xu, Cheng; Sun, Wei; Zhao, Erhu; Wang, Min; Reis, R. L.; Kundu, Subhas C; Shi, Xiaoxiao

The therapeutic outcomes of conventional oral medications against ulcerative colitis (UC) are restricted by inefficient drug delivery to the colitis mucosa and weak capacity to modulate the inflammatory microenvironment. Herein, a fluorinated pluronic (FP127) was synthesized and employed to functionalize the surface of mulberry leaf-derived nanoparticles (MLNs) loading with resveratrol nanocrystals (RNs). The o...


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