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The European Reference Genome Atlas: piloting a decentralised approach to equit...

Mc Cartney, Ann M.; Formenti, Giulio; Mouton, Alice; De Panis, Diego; Marins, Luísa S.; Leitão, Henrique G.; Diedericks, Genevieve; Kirangwa, Joseph

A genomic database of all Earth’s eukaryotic species could contribute to many scientific discoveries; however, only a tiny fraction of species have genomic information available. In 2018, scientists across the world united under the Earth BioGenome Project (EBP), aiming to produce a database of high-quality reference genomes containing all ~1.5 million recognized eukaryotic species. As the European node of the ...


The European Reference Genome Atlas: piloting a decentralised approach to equit...

Mc Cartney, Ann M.; Formenti, Giulio; Mouton, Alice; De Panis, Diego; Marins, Luísa S.; Leitão, Henrique G.; Diedericks, Genevieve; Kirangwa, Joseph

A genomic database of all Earth’s eukaryotic species could contribute to many scientific discoveries; however, only a tiny fraction of species have genomic information available. In 2018, scientists across the world united under the Earth BioGenome Project (EBP), aiming to produce a database of high-quality reference genomes containing all ~1.5 million recognized eukaryotic species. As the European node of the ...


To be, or not to be: that is the hamletic question of cryptic evolution in the ...

Ferrari, Alice; Crobe, Valentina; Cannas, Rita; Leslie, Rob W.; Serena, Fabrizio; Stagioni, Marco; Costa, Filipe O.; Golani, Daniel; Hemida, Farid

Despite a high species diversity, skates (Rajiformes) exhibit remarkably conservative morphology and ecology. Limited trait variations occur within and between species, and cryptic species have been reported among sister and non-sister taxa, suggesting that species complexes may be subject to stabilising selection. Three sibling species are currently recognised in the Raja miraletus complex: (i) R. miraletus oc...


Natural history and molecular evolution of demersal Mediterranean sharks and sk...

Ferrari, Alice; Tinti, Fausto; Maresca, Victoria Bertucci; Velonà, Alessandro; Cannas, Rita; Thasitis, Ioannis; Costa, Filipe O.

Background. The unique and complex paleoclimatic and paleogeographic events which affected the Mediterranean Sea since late Miocene deeply influenced the distribution and evolution of marine organisms and shaped their genetic structure. Following the Messinian salinity crisis and the sea-level fluctuations during the Pleistocene, several Mediterranean marine species developed deep genetic differentiation, and s...


Quaternary geographical sibling speciation and population structuring in the Ea...

Pasolini, Paola; Ragazzini, Chiara; Zaccaro, Zelia; Cariani, Alessia; Ferrara, Giorgia; Gonzalez, Elena G.; Landi, Monica; Milano, Ilaria

Aim Geographical (allopatric) speciation is a dynamic process whose footprints in the living world are a continuum of stages of increasing divergence. Geographical speciation can also contribute to the evolution of marine taxa. This study looked for two of these evolutionary stages (i.e. structured populations and sibling species) in the diversification patterns of two Atlantic skates (Raja, suborder Rajoidea) ...


Spatio-temporal population structuring and genetic diversity retention in deple...

Riccioni, Giulia; Landi, Monica; Ferrara, Giorgia; Milano, Ilaria; Cariani, Alessia; Zane, Lorenzo; Sella, Massimo; Barbujani, Guido; Tinti, Fausto

There are a number of challenges associated with designing nanoparticles for medical applications. We define two challenges here: (i) conventional targeting against up-regulated cell surface antigens is limited by heterogeneity in expression, and (ii) previous studies suggest that the optimal size of nanoparticles designed for systemic delivery is approximately 50–150 nm, yet this size range confers a high surf...


Identifying Fishes through DNA barcodes and microarrays

Kochzius, Marc; Seidel, Christian; Aglaia, Antoniou; Botla, Sandeep Kumar; Campo, Daniel; Cariani, Alessia; Garcia Vazquez, Eva; Hauschild, Janet

Background: International fish trade reached an import value of 62.8 billion Euro in 2006, of which 44.6 % are covered by the European Union. Species identification is a key problem throughout the life cycle of fishes: from eggs and larvae to adults in fisheries research and control, as well as processed fish products in consumer protection.


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