15 documents found, page 1 of 2
Serum inflammatory biomarkers are associated with increased choroidal thickness...
Pinheiro-Costa, J; Fontes, ML; Luís, C; Martins, S; Soares, R; Madeira, D; Falcao-Reis, F; Carneiro, AInflammation may play a significant role in Keratoconus (KC), but the relationship between inflammatory markers and choroidal thickness (CT) is unknown. The purpose of this study was to evaluate serum inflammatory markers and correlate them with the choroidal profile of KC patients and control subjects. Forty patients with KC and 26 age-matched control subjects were enrolled in a cross-sectional case-control st...
Fly and Treat: Endovascular Treatment of Ruptured Aneurysms at an Insular Terti...
Almeida Xavier, S; Rodrigues, A; Meira, T; Mota Dória, H; Figueira, C; Amorim, J; Pestana, R; Nobrega, J; Franco, J; Carneiro, A(Objectives) Aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening condition associated with poor outcomes. Early intervention is critical, particularly in low-volume hospitals, which are advised to transfer aSAH patients to high-volume centers. This study examines a novel protocol implemented in 2016 at Região Autónoma da Madeira, a Portuguese island. It involves the mobilization of experienced neuro...
Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal
Carvalho Dias, M; Soares dos Reis, R; Santos, JV; Paiva Nunes, A; Ferreira, P; Maia, B; Fragata, I; Reis, J; Ramos Lopes, J; Cruz, L; Santo, GIntroduction: Since the publication of endovascular treatment trials and European Stroke Guidelines, Portugal has re-organized stroke healthcare. The nine centers performing endovascular treatment are not equally distributed within the country, which may lead to differential access to endovascular treatment. Our main aim was to perform a descriptive analysis of the main treatment metrics regarding endovascular ...
Choroidal Vascular Impairment in Intermediate Age-Related Macular Degeneration
Flores, R; Carneiro, A; Neri, G; Fradinho, A; Quenderra, B; Barata, MJ; Tenreiro, S; Seabra, MAge-related macular degeneration (AMD) is a multifactorial disease, whose complete pathogenesis is still unclear. Local hemodynamics may play a crucial role in its manifestation and progression. To evaluate choroidal and retinal vascular parameters, a total of 134 eyes were analyzed, 100 with intermediate AMD and 34 age matched healthy controls. 131 eyes of 104 patients were eligible for complete image assessme...
Retinal Progression Biomarkers of Early and Intermediate Age-Related Macular De...
Flores, R; Carneiro, A; Tenreiro, S; Seabra, MCEarly and intermediate AMD patients represent a heterogeneous population with an important but variable risk of progression to more advanced stages of the disease. The five-year progression from early and intermediate AMD to late disease is known to range from 0.4% to 53%. This wide variation explains the particular interest in searching predictive AMD biomarkers. Clinical parameters such as drusen size, presen...
Guidelines for the Management of Center-Involving Diabetic Macular Edema: Treat...
Figueira, J; Henriques, J; Carneiro, A; Marques-Neves, C; Flores, R; Castro-Sousa, JP; Meireles, A; Gomes, N; Nascimento, J; Amaro, M; Silva, RDiabetic macular edema (DME) is the main cause of visual impairment associated with diabetic retinopathy (DR) and macular laser, during approximately three decades, and was the single treatment option. More recently, intravitreous injections of anti-angiogenics and corticosteroids modified the treatment paradigm associated with significant vision improvements. Nevertheless, not all patients respond satisfactori...
A Potentially Fatal Aphrodisiac: Cantharidin Poisoning
Diaz, P; Carneiro, A; Montes, V; Alves, SCantharidin is a toxin extracted from coleoptera beetles, commonly known as 'Spanish fly'. Traditionally it was used as an aphrodisiac, a vesicant or as an abortifacient. Intoxication by this substance has been widely reported, generally associated with gastrointestinal complications, such as digestive hemorrhage, and genitourinary disorders, such as hematuria and acute kidney injury. The authors describe the c...
Um Afrodisíaco Potencialmente Fatal: Intoxicação por Cantaridina
Diaz, P; Carneiro, A; Montes, V; Alves, SCantharidin is a toxin extracted from coleoptera beetles, commonly known as 'Spanish fly'. Traditionally it was used as an aphrodisiac, a vesicant or as an abortifacient. Intoxication by this substance has been widely reported, generally associated with gastrointestinal complications, such as digestive hemorrhage, and genitourinary disorders, such as hematuria and acute kidney injury. The authors describe the c...
Um Afrodisíaco Potencialmente Fatal: Intoxicação por Cantaridina
Diaz, P; Carneiro, A; Montes, V; Alves, SCantharidin is a toxin extracted from coleoptera beetles, commonly known as 'Spanish fly'. Traditionally it was used as an aphrodisiac, a vesicant or as an abortifacient. Intoxication by this substance has been widely reported, generally associated with gastrointestinal complications, such as digestive hemorrhage, and genitourinary disorders, such as hematuria and acute kidney injury. The authors describe the c...
A Retrospective Analysis of the Real-Life Utilization of Ranibizumab in Patient...
Silva, R; Goncalves, C; Meireles, A; Teixeira, C; Rosa, P; Monteiro-Grillo, M; Canelas, J; Carneiro, A; Flores, RINTRODUCTION: Anti-vascular endothelial growth factor therapy has revolutionized the treatment of wet age-related macular degeneration; however, it is important to monitor actual use of ranibizumab and related treatment outcomes in routine practice. MATERIAL AND METHODS: This was a retrospective, observational study to monitor the 2-year outcomes following ranibizumab treatment for wet age-related macular degen...