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Surgical Resection of Multiple Small Bowel Neuroendocrine Tumours Using Intraop...

Rafael, MA; Rocha, R; Oliveira, AM; Rodrigues, C; Carneiro, C; Nunes, V


Bladder Cancer New Biomarkers in Liquid Biopsies

Falcão, G; Barreira, JV; Parmanande, A; Carneiro, C; Campos Pinheiro, L

Bladder cancer is one of the most common neoplasia in men in the developed countries. Diagnosis and surveillance are made by bladder examination through cystoscopy making this one of the most expensive on cost/patient. After tumor removal, clinical staging is important for prognosis and treatment decision as non-muscle invasive (Ta and T1) and invasive (T2+) are treated in a completely different way. Today no n...


Successful treatment of severe perianal Crohn's disease with infliximab in an H...

Rafael, MA; Lourenço, L; Oliveira, AM; Branco, T; Carneiro, C; Costa, A; Reis, J

Perianal inflammation is a disabling manifestation of Crohn's disease. The primary lesions found in perianal Crohn's disease evolve in parallel with the disease elsewhere in the bowel. Although the spontaneous resolution of anal lesions is observed in up to half of patients, the penetrating nature of the disease may lead to secondary lesions including complex fistulae. In some patients, this, in turn, results i...


Amputação abdominoperineal extraelevador – Revisão

Carneiro, C; Rocha, R; Marinho, R; Leichsenring, C; Geraldes, V; Nunes, V

Desde a descrição da Excisão Total do Mesorecto (ETM), a taxa de recidiva local da neoplasia do recto submetida a ETM decresceu consideravelmente para valores entre os 5 e 15%. No entanto, no que diz respeito à neoplasia do recto tratada cirurgicamente com amputação abdominoperineal (AAP), esta taxa manteve-se na ordem dos 40%. Os fatores identificados como responsáveis por estes piores resultados oncológicos f...


Actinomycosis Causing Recurrent Perianal Fistulae

Cardoso, M; Carneiro, C; Lourenço, L; Rodrigues, C; Alberto, S; João, A; Rocha, R; Geraldes, V; Costa, A; Reis, J; Nunes, V

Actinomycosis is a rare but easily curable infection that should be considered in the differential diagnosis of perianal fistulizing disease. We present the case of a 26-year-old woman with complex perianal fistulae, including trans-sphincteric and suprasphincteric fistulous tracts and a rectovaginal fistula, requiring multiple abscess drainages, seton placement, and antibiotic courses, with little improvement....


Spontaneous Rupture of Pancreatic Pseudocyst: Report of Two Cases.

Rocha, R; Marinho, R; Gomes, A; Sousa, M; Pignatelli, N; Carneiro, C; Nunes, V

Introduction. Pancreatic pseudocysts are a common complication of acute pancreatitis. Pancreatic pseudocyst's natural history ranges between its spontaneous regression and the settlement of serious complications if untreated, such as splenic complications, hemorrhage, infection, biliary complications, portal hypertension, and rupture. The rupture of a pancreatic pseudocyst to the peritoneal cavity is a dangerou...


Impact of bowel resection margins in node negative colon cancer.

Rocha, R; Marinho, R; Aparício, D; Fragoso, M; Sousa, M; Gomes, A; Leichsenring, C; Carneiro, C; Geraldes, V; Nunes, V

Surgical intestinal resection margins in colon cancer are a longstanding debate in terms the optimal distance between the tumor and the colonic section line. The aim of this study is to define the oncological outcomes in relation to surgical margins, measured in terms or recurrence rate, time-to-recurrence, disease-free survival and overall survival in a population of node negative colon cancer patients. METHOD...


Retalho V-Y bilateral para reconstrução do períneo após amputação abdomino-peri...

Rocha, R; Carneiro, C; João, A; Soares, A; Aparício, D; Fragoso, M; Marinho, R; Sousa, M; Leichsenring, C; Geraldes, V; Nunes, V

A descrição da amputação abdominoperineal extraelevadora (ELAPE) para a ressecção de tumores do recto baixo ou da margem anal, a subsequente estandardização do tempo perineal e a definição das suas indicações precisas, veio colocar enfâse particular na necessidade de recorrer a técnicas de reconstrução do períneo para encerramento dos defeitos perineais provocados por ressecções mais alargadas. Apresentamos um ...


Excisão completa do mesocólon – revisão da literatura

Carneiro, C; Rocha, R; Marinho, R; Gomes, A; Leichsenring, C; Geraldes, V; Nunes, V

Desde a descrição da Excisão Total do Mesorreto (TME), a taxa de recidiva local da neoplasia do recto desceu de 20 a 40% para cerca de 10%(1,2). É neste contexto, que Hohenberger descreve em 2008 a Excisão Completa do Mesocólon (Complete Mesocolic Excision, CME)(3). Trata-se de uma técnica cirúrgica mais radical, tendo como base teórica e conceptual os mesmos princípios descritos por Heald para a TME. Com a CME...


Colorectal surgical mortality and morbidity in elderly patients: comparison of ...

Gomes, A; Rocha, R; Marinho, R; Sousa, M; Pignatelli, N; Carneiro, C; Nunes, V

PURPOSE: This study aims to compare the predictive value of POSSUM, P-POSSUM, CR-POSSUM and CR-BHOM in colorectal surgical mortality and morbidity in patients over 80 years old. METHODS: This is a retrospective observational longitudinal study. A total of 991 patients who underwent major colorectal surgery between 2008 and 2012 in a secondary hospital in Portugal were screened, and 204 who were over 80 years ol...


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