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Influência do mecanismo de quorum sensing no metabolismo de Salmonella enterica

Carneiro, Deisy Guimarães

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Salmonella é um dos principais patógenos que causam infecções relacionadas ao consumo de alimentos contaminados. Salmonella enterica sorotipo Enteritidis (Salmonella Enteritidis) é mais comumente associado a surtos clínicos em vários países, incluindo no Brasil. Por meio do mecanismo de quorum sensing (QS), esse patógeno é capaz de coordenar seu perfi...

Date: 2018   |   Origin: Oasisbr

N-dodecanoyl-homoserine lactone influences the levels of thiol and proteins rel...

Almeida, Felipe Alves de; Carneiro, Deisy Guimarães; Barros, Edvaldo; Pinto, Uelinton Manoel; Oliveira, Leandro Licursi de

Quorum sensing is a cell-cell communication mechanism mediated by chemical signals that leads to differential gene expression in response to high population density. Salmonella is unable to synthesize the autoinducer-1 (AI-1), N-acyl homoserine lactone (AHL), but is able to recognize AHLs produced by other microorganisms through SdiA protein. This study aimed to evaluate the fatty acid and protein profiles of S...

Date: 2018   |   Origin: Oasisbr

Virtual screening of plant compounds and nonsteroidal anti-inflammatory drugs f...

Almeida, Felipe Alves de; Vargas, Erika Lorena Giraldo; Carneiro, Deisy Guimarães; Pinto, Uelinton Manoel; Vanetti, Maria Cristina Dantas

Salmonella belongs to the Enterobacteriaceae family which is widely distributed in the environment due to its adaptive capacity to stress conditions. In addition, Salmonella is able to perform a type of cell-to-cell communication called quorum sensing, which leads to differential gene expression. The quorum sensing system mediated by AI-1, acyl homoserine lactones (AHLs), is incomplete in Salmonella because the...

Date: 2018   |   Origin: Oasisbr

Applying functional metagenomics to search for novel lignocellulosic enzymes in...

Colombo, Lívia Tavares; Oliveira, Marcelo Nagem Valério de; Carneiro, Deisy Guimarães; Souza, Robson Assis de; Alvim, Mariana Caroline Tocantins

Environments where lignocellulosic biomass is naturally decomposed are sources for discovery of new hydrolytic enzymes that can reduce the high cost of enzymatic cocktails for second-generation ethanol production. Metagenomic analysis was applied to discover genes coding carbohydrate-depleting enzymes from a microbial laboratory subculture using a mix of sugarcane bagasse and cow manure in the thermophilic comp...

Date: 2018   |   Origin: Oasisbr

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