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Epigallocathechin-O-3-Gallate Inhibits Trypanothione Reductase of Leishmania in...

Inacio, JDF; Fonseca, MS; Limaverde-Sousa, G; Tomás, AM; Castro, H; Almeida-Amaral, EE

Leishmania infantum is a protozoan parasite that causes a vector borne infectious disease in humans known as visceral leishmaniasis (VL). This pathology, also caused by L. donovani, presently impacts the health of 500,000 people worldwide, and is treated with outdated anti-parasitic drugs that suffer from poor treatment regimens, severe side effects, high cost and/or emergence of resistant parasites. In previou...

Date: 2021   |   Origin: Repositório Aberto da Universidade do Porto
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