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The Role of Self-Collection by Vaginal Lavage for the Detection of HPV and High...
Kuil, Larissa de Melo; Lorenzi, Adriana Tarla; Stein, Maíra Degiovani; Resende, Júlio César Possati; Antoniazzi, Márcio; Longatto Filho, AdhemarObjective: To compare the results of cervical cytology and high-risk HPV tests using samples obtained using two different collection modalities in a population of Brazilian women: self-collection (vaginal lavage) and cervical Pap testing. Methods: We enrolled 204 women who were aged 18-64 years and had previously obtained abnormal cervical cytology test results; 83.8% of them agreed to participate. The sample w...
Low mutation percentage of KRAS and BRAF genes in Brazilian anal tumors
Bidinotto, Lucas Tadeu; Veo, Carlos A. R.; Loaiza, Edgar Antonio Alemán; França, Alessandra Paulino Santos de; Lorenzi, Adriana TarlaAnal cancer is a rare type of digestive tract disease, which has had a crescent incidence in a number of regions. Carcinomas are most frequently found, with squamous cell carcinoma (SCC) comprising similar to 95% of all anal tumors. The major risk factor for development of this type of tumor is human papillomavirus (HPV) infection. However, previous studies have identified patients with anal cancer that are HPV...