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Hyperoside Supplementation in Preservation Media Surpasses Vitamin C Protection...

Moreira, MV; Pereira, SC; Guerra-Carvalho, B; Carrageta, DF; Pinto, S; Barros, A; Silva, BM; Oliveira, PF; Alves, MG

Background/Aims: Oxidative Stress (OS) is reported as one of the main causes of male infertility. Infertile couples often resort to assisted reproductive technology (ART) to achieve parenthood. However, preparation for ART protocols increases the exposer of gametes to OS. Thus, it is crucial to find suitable preservation media that can counteract the OS-induced damages in spermatozoa. In this work, we tested an...


Mitochondrial activation and reactive oxygen-species overproduction during sper...

Carrageta, DF; Guerra-Carvalho, B; Sousa, M; Barros, A; Oliveira, PF; Monteiro, MP; Alves, MG

Spermatozoa capacitation is a complex process that requires specific ionic and energetic conditions to support biochemical alterations leading to motility hyperactivation. However, human sperm capacitation is still poorly understood. Herein, we studied the effects of glucose on human sperm capacitation. Healthy men seminal samples (n = 55) were submitted to a density gradient centrifugation and incubated in cap...


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