2 documents found, page 1 of 1
Hyperoside Supplementation in Preservation Media Surpasses Vitamin C Protection...
Moreira, Mafalda V; Pereira, Sara C; Guerra-Carvalho, Bárbara; Carrageta, David F; Pinto, Soraia; Barros, Alberto; Silva, Branca M.; Oliveira, Pedro F.Oxidative Stress (OS) is reported as one of the main causes of male infertility. Infertile couples often resort to assisted reproductive technology (ART) to achieve parenthood. However, preparation for ART protocols increases the exposer of gametes to OS. Thus, it is crucial to find suitable preservation media that can counteract the OS-induced damages in spermatozoa. In this work, we tested and compared the ef...
8-(3-phenylpropyl)-1,3,7-triethylxanthine is a synthetic caffeine substitute wi...
Carrageta, David F; Dias, Tânia R.; Jarak, Ivana; Alves, Marco G; Oliveira, P.F.; Walt, Mietha Van Der; Terre'Blanche, Gisella; Monteiro, Mariana P.Caffeine is one of the most worldwide consumed methylxanthines. It is well-known for its thermogenic and cell metabolism modulating effects. Based on methylxanthines' chemical structure, 8-(3-phenylpropyl)-1,3,7-triethylxanthine (PTX) is a novel adenosine antagonist with higher receptor affinity than caffeine. Therefore, we hypothesized that PTX metabolic effects could be stronger than those of caffeine. For th...