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Dual-loaded chitosan-based nanoparticles: a novel approach for treating polymic...
Zegre, Miguel; Barros, J.; David, A. B.; Fialho, L.; Ferraz, M. P.; Monteiro, F. J.; Caetano, Liliana Aranha; Gonçalves, L.; Bettencourt, A.Developing innovative approaches to target osteomyelitis caused by polymicrobial infections remains a significant therapeutic challenge. In this study, monodispersed chitosan nanoparticles co-loaded with antibacterial (minocycline) and antifungal (voriconazole) agents were successfully prepared. Minocycline presented higher encapsulation efficiency as compared to voriconazole. Thermostability analysis suggested...
Boosting knowledge on occupational exposure to microbial contamination in Portu...
Dias, Marta; Gomes, Bianca; Pena, Pedro; Cervantes, Renata; Rodriguez, Margarida; Riesenberger, Bruna; Marques, Liliana; Carolino, ElisabeteIntroduction: Wood industry workers face health risks due to exposure to microorganisms and their metabolites. This study aimed to characterize seasonal microbial contamination, antifungal resistance, mycotoxins, cytotoxicity, and particulate matter in Portuguese carpentries, to reduce exposure and promote safe working conditions. Methods: Conducted in six carpentries in Lisbon, Portugal, the sampling strategy ...
Poultry farms as reservoirs of azole-resistant fungi: occupational health risks...
Gomes, Bianca; Dias, Marta; Cervantes, Renata; Pena, Pedro; Carolino, Elisabete; Caetano, Liliana Aranha; Viegas, Susana; Viegas, CarlaThe intensification of poultry farming has raised concerns regarding microbial contamination and antifungal resistance, particularly involving Aspergillus fumigatus, a key pathogen presenting clinical relevance. This study aims to present the first in-depth evaluation of environmental conditions, airborne particles, microbial contamination, and fungal resistance to azole drugs in poultry farm environments. A mu...
Fungal and mycotoxins contamination in non-alcoholic beverages: the case of tea...
Viegas, Carla; Gomes, Bianca; Cervantes, Renata; Dias, Marta; Pena, Pedro; Oliveira, Filipe; Andrade, Ednilton Tavares de; Caetano, Liliana AranhaAgriculture constitutes one of the most sensitive sectors that could be affected by climate change. Among the xenobiotics contaminating agricultural crops, fungi and mycotoxins are the most challenging since their presence represents an economic burden due to crop loss and serious health effects related to animals and humans with severe repercussions. This study intends to characterize the fungal and mycotoxin ...
Microbial assessment in a rare Norwegian book collection: a One Health approach...
Sequeira, Sílvia O.; Pasnak, Ekaterina; Viegas, Carla; Gomes, Bianca; Dias, Marta; Cervantes, Renata; Pena, Pedro; Twarużek, Magdalena; Kosicki, RobertMicrobial contamination poses a threat to both the preservation of library and archival collections and the health of staff and users. This study investigated the microbial communities and potential health risks associated with the UNESCO-classified Norwegian Sea Trade Archive (NST Archive) collection exhibiting visible microbial colonization and staff health concerns. Dust samples from book surfaces and the st...
Portuguese cork industry: filling the knowledge gap regarding occupational expo...
Viegas, Carla; Dias, Marta; Pacífico, Cátia; Faria, Tiago; Clérigo, Anália Matos; Dias, Hermínia Brites; Caetano, Liliana Aranha; Carolino, ElisabeteIntroduction: The presence of the Penicillium section Aspergilloides (formerly known as Penicillium glabrum) in the cork industry involves the risk of respiratory diseases such as suberosis. Methods: This study aimed to corroborate the predominant fungi presents in this occupational environment by performing a mycological analysis of 360 workers’ nasal exudates collected by nasal swabs. Additionally, evaluation...
Assessment of the microbial contamination in 'Do It Yourself' (DIY) stores: a h...
Dias, Marta; Gomes, Bianca; Pena, Pedro; Cervantes, Renata; Gonçalves, Sara; Carolino, Elisabete; Twarużek, Magdalena; Kosicki, Robert; Ałtyn, IwonaIntroduction: In “Do-It-Yourself” (DIY) stores, workers from the wood department are considered woodworkers. Given the health risks associated with woodworking, particularly from fungi and their metabolites, this study aims to assess microbial contamination and health risks for both workers and customers. Methods: The study was developed in 13 DIY stores in the Lisbon Metropolitan Area, Portugal. It employed a ...
Assessment of Portuguese fitness centers: bridging the knowledge gap on harmful...
Viegas, Carla; Peixoto, Cátia; Gomes, Bianca; Dias, Marta; Cervantes, Renata; Pena, Pedro; Slezakova, Klara; Pereira, Maria do Carmo; Morais, SimoneThe lack of knowledge regarding the extent of microbial contamination in Portuguese fitness centers (FC) puts attendees and athletes at risk for bioaerosol exposure. This study intends to characterize microbial contamination in Portuguese FC by passive sampling methods: electrostatic dust collectors (EDC) (N=39), settled dust (N=8), vacuum filters (N=8), and used cleaning mops (N=12). The obtained extracts were...
Microbial occupational exposure in e-waste recycling: biological hazards, their...
Viegas, Carla; Gomes, Bianca; Dias, Marta; Cervantes, Renata; Pena, Pedro; Gonçalves, Sara; Almeida-Silva, Marina; Carolino, ElisabeteE-waste management is a major environmental concern that also poses serious risks to occupational health. While e-waste workers are exposed to a variety of chemicals, little is known about occupational exposure to microbiological agents. This study aims to fill that gap. For that purpose, two e-waste facilities were assessed: one battery-recycling facility (BRF), and another facility (SRE) dedicated to e-waste ...
Microbial occupational exposure in e-waste recycling: biological hazards, their...
Viegas, Carla; Gomes, Bianca; Dias, Marta; Cervantes, Renata; Pena, Pedro; Gonçalves, Sara; Almeida-Silva, Marina; Carolino, ElisabeteE-waste management is a major environmental concern that also poses serious risks to occupational health. While e-waste workers are exposed to a variety of chemicals, little is known about occupational exposure to microbiological agents. This study aims to fill that gap. For that purpose, two e-waste facilities were assessed: one battery-recycling facility (BRF), and another facility (SRE) dedicated to e-waste ...