6 documents found, page 1 of 1
O papel da criobiópsia nas doenças intersticiais
Carreto, L; Luz, I; Rodrigues, F
Utility of routine screening for alpha-1 antitrypsin deficiency in patients wit...
Carreto, L; Morrison, M; Donovan, J; Finch, S; Tan, GL; Fardon, T, et al.Alpha-1 antitrypsin deficiency (AATD) is a cause of bronchiectasis. Guidelines for bronchiectasis from the British Thoracic Society do not recommend to routinely test patients for AATD. In contrast, guidelines for AATD recommend routine screening. This contradiction, in part, results from the lack of data from large studies performing comprehensive screening. We screened 1600 patients with bronchiectasis at two...
Admission of Lung Cancer Patients to Intensive Care Units
Carreto, L; Simão, C; Silveira, M; Almeida, MA
A point-of-care neutrophil elastase activity assay identifies bronchiectasis se...
Shoemark, A; Cant, E; Carreto, L; Smith, A; Oriano, M; Keir, HR, et al.Abstract INTRODUCTION: Neutrophil elastase activity in sputum can identify patients at high risk of airway infection and exacerbations in bronchiectasis. Application of this biomarker in clinical practice is limited, because no point-of-care test is available. We tested whether a novel semi-quantitative lateral flow device (neutrophil elastase airway test stick - NEATstik®) can stratify bronchiectasis patients ...
Lung Adenocarcinoma Presenting as a Multiple Cavitary Disease
Carreto, L; Alves, C; Eurico, J; Cavinho, P
Interstitial Lung Disease Induced by Crizotinib in Non-Small-Cell Lung Cancer.
Tereso, A; Carreto, L; Baptista, M; Almeida, MAThe treatment of advanced non-small-cell lung cancer shifted with the development of molecular-targeted therapies, like the tyrosine kinase inhibitors. One example of tyrosine kinase inhibitors is crizotinib, an anaplastic lymphoma tyrosine kinase inhibitor, which targets an echinoderm microtubule-associated protein-like-4-anaplastic lymphoma kinase gene fusion. This mutation is found in only 2% to 7% of non-sm...