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Incidental adrenal mass: is 4 cm a good cut-off for surgical decision?

Carvalho, J; Nunes, P; Antunes, H; Parada, B; Retroz, E; Tavares da Silva, E; Carrilho, F; Figueiredo, A


Transumbilical approach for laparoendoscopic single-site adrenalectomy: Why not?

Carvalho, J; Nunes, P; Antunes, H; Parada, B; Retroz, E; Tavares da Silva, E; Carrilho, F; Figueiredo, A


Controversies in the management of hyperglycaemic emergencies in adults with di...

Cardoso, L; Vicente, N; Rodrigues, D; Gomes, L; Carrilho, F

Hyperglycaemic emergencies are associated with significant morbi-mortality and healthcare costs. Management consists on fluid replacement, insulin therapy, and electrolyte correction. However, some areas of patient management remain debatable. In patients without respiratory failure or haemodynamic instability, arterial and venous pH and bicarbonate measurements are comparable. Fluid choice varies upon replenis...


Adrenalectomia parcial laparoscópica – será que vale a pena o esforço?

Carvalho, J; Nunes, P; Antunes, H; Parada, B; Tavares da Silva, E; Retroz, E; Carrilho, F; Figueiredo, A


Nódulos incidentais da glândula suprarrenal: a experiência de um serviço de uro...

Carvalho, J; Nunes, P; Antunes, H; Parada, B; Tavares da Silva, E; Retroz, E; Carrilho, F; Figueiredo, A


Será a adrenalectomia por porta única umbilical uma alternativa credível à adre...

Carvalho, J; Nunes, P; Antunes, H; Parada, B; Retroz, E; Tavares da Silva, E; Carrilho, F; Figueiredo, A


Long-term survival in a patient with brain metastases of papillary thyroid carc...

Guelho, D; Ribeiro, C; Melo, M; Carrilho, F

We present the case of a 43-year-old woman who underwent total thyroidectomy with bilateral lymphadenectomy for a papillary thyroid carcinoma (PTC), solid variant (T4bN1bMx), with V600E BRAF mutation. After ablative therapy, she presented undetectable thyroglobulin (Tg) but progressively increasing anti-Tg antibodies (TgAbs). During follow-up, nodal, lung and brain metastases were identified. She was submitted ...


Relations between Cardiac and Visual Phenotypes in Diabetes: A Multivariate App...

Oliveiros, B; Sanches, M; Quendera, B; Graça, B; Guelho, D; Gomes, L; Carrilho, F; Caseiro-Alves, F; Castelo-Branco, M

Cardiovascular disease and diabetes represent a major public health concern. The former is the most frequent cause of death and disability in patients with type 2 diabetes, where left ventricular dysfunction is highly prevalent. Moreover, diabetic retinopathy is becoming a dominant cause of visual impairment and blindness. The complex relation between cardiovascular disease and diabetic retinopathy as a functio...


Agonistas dos Receptores do GLP-1 no Tratamento da Diabetes Tipo 2

Carvalho, D; Silva Nunes, J; Raposo, J; Medina, J; Jácome de Castro, J; Carrilho, F

A Diabetes Mellitus tipo 2 é um flagelo individual, social e económico, em particular nas sociedades ocidentais. A metformina surge como fármaco de primeira linha na terapêutica farmacológica desta patologia, mas na impossibilidade de controlo metabólico adequado sob esta em monoterapia, as recomendações colocam as restantes classes de fármacos ao mesmo nível, reflectindo uma mudança de paradigma para a individ...


Early disrupted neurovascular coupling and changed event level hemodynamic resp...

Duarte, JV; Pereira, JM; Quendera, B; Raimundo, M; Moreno, C; Gomes, L; Carrilho, F; Castelo-Branco, M

Type 2 diabetes (T2DM) patients develop vascular complications and have increased risk for neurophysiological impairment. Vascular pathophysiology may alter the blood flow regulation in cerebral microvasculature, affecting neurovascular coupling. Reduced fMRI signal can result from decreased neuronal activation or disrupted neurovascular coupling. The uncertainty about pathophysiological mechanisms (neurodegene...


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