29 documents found, page 1 of 3
Late-Night Salivary Cortisol: Cut-Off Definition and Diagnostic Accuracy for Cu...
Lages, Adriana Sousa; Frade, João Gonçalo; Oliveira, Diana; Paiva, Isabel; Oliveira, Patrícia; Rebelo-Marques, Alexandre; Carrilho, FranciscoIntroduction: Diagnosis of Cushing’s syndrome remains a challenge in clinical endocrinology. Even though late-night salivary cortisol is used as screening tool, individualized cut-off levels for each population must be defined. Material and Methods: Three groups of subjects were studied: normal subjects, suspected and proven Cushing’s syndrome. Salivary cortisol was measured using an automated electrochemilumin...
Impacto do Uso Prolongado da Terapêutica Subcutânea Contínua com Insulina no Co...
Azevedo, Sérgio; Saraiva, Joana; Caramelo, Francisco; Fadiga, Lúcia; Barros, Luisa; Baptista, Carla; Melo, Miguel; Gomes, Leonor; Carrilho, FranciscoIntrodução: O uso da terapêutica com perfusão subcutânea contínua de insulina na diabetes mellitus tipo 1 é cada vez mais frequente devido aos seus efeitos benéficos no controlo glicémico e na flexibilidade do estilo de vida. Constituiu objetivo deste estudo avaliar o impacto da terapêutica com perfusão subcutânea contínua de insulina no controlo glicémico, índice de massa corporal, dose diária total de insulin...
The Impact of Prolonged Use of Continuous Subcutaneous Insulin Infusion in the ...
Azevedo, Sérgio; Saraiva, Joana; Caramelo, Francisco; Fadiga, Lúcia; Barros, Luísa; Baptista, Carla; Melo, Miguel; Gomes, Leonor; Carrilho, FranciscoIntroduction: The use of continuous subcutaneous insulin infusion therapy in type 1 diabetes mellitus has increased due to its benefits on glycemic control and on the lifestyle flexibility. The aim of this study was to assess the impact of continuous subcutaneous insulin infusion therapy on glycemic control, body mass index, total daily dose of insulin and complications associated with this therapy, during 20 y...
Late-Night Salivary Cortisol: Cut-Off Definition and Diagnostic Accuracy for Cu...
Lages, Adriana De Sousa; Frade, João Gonçalo; Oliveira, Diana; Paiva, Isabel; Oliveira, Patrícia; Rebelo-Marques, Alexandre; Carrilho, FranciscoIntroduction: Diagnosis of Cushing’s syndrome remains a challenge in clinical endocrinology. Even though late-night salivary cortisol is used as screening tool, individualized cut-off levels for each population must be defined.Material and Methods: Three groups of subjects were studied: normal subjects, suspected and proven Cushing’s syndrome. Salivary cortisol was measured using an automated electrochemilumine...
Late-Night Salivary Cortisol: Cut-Off Definition and Diagnostic Accuracy for Cu...
Lages, Adriana De Sousa; Oliveira, Diana; Paiva , Isabel; Oliveira, Patrícia; Rebelo-Marques, Alexandre; Carrilho, FranciscoIntroduction: Diagnosis of Cushing’s syndrome remains a challenge in clinical endocrinology. Even though late-night salivary cortisol is used as screening tool, individualized cut-off levels for each population must be defined.Material and Methods: Three groups of subjects were studied: normal subjects, suspected and proven Cushing’s syndrome. Salivary cortisol was measured using an automated electrochemilumine...
Dental caries and bacterial load in saliva and dental biofilm of type 1 diabeti...
Coelho, Ana; Paula, Anabela; Mota, Marta; Laranjo, Mafalda; Abrantes, Margarida; Carrilho, Francisco; Ferreira, Manuel; Silva, Mário; Botelho, FilomenaObjectives: Since most of the studies evaluates diabetics on multiple daily injections therapy and continuous subcutaneous insulin infusion may help gain better metabolic control and prevent complications, the objective of this study was to evaluate the prevalence of dental caries, the unstimulated salivary flow rate and the total bacteria load, Streptococcus spp. levels and Lactobacillus spp. levels in saliva ...
Aging Hallmarks: The Benefits of Physical Exercise
Rebelo-Marques, Alexandre; Lages, Adriana De Sousa; Andrade, Renato; Ribeiro, Carlos Fontes; Mota-Pinto, Anabela; Carrilho, FranciscoWorld population has been continuously increasing and progressively aging. Aging is characterized by a complex and intraindividual process associated with nine major cellular and molecular hallmarks, namely, genomic instability, telomere attrition, epigenetic alterations, a loss of proteostasis, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered inter...
Aging Hallmarks: the benefits of physical exercise
Rebelo-Marques, Alexandre; De Sousa Lages, Adriana; Andrade, Renato; Ribeiro, Carlos Fontes; Mota-Pinto, Anabela; Carrilho, FranciscoWorld population has been continuously increasing and progressively aging. Aging is characterized by a complex and intraindividual process associated with nine major cellular and molecular hallmarks, namely, genomic instability, telomere attrition, epigenetic alterations, a loss of proteostasis, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered inter...
Prevalência de Lesões de Cárie de Doentes com Diabetes Mellitus Tipo 1 Tratados...
Machado, Diogo; Coelho, Ana; Paula, Anabela; Caramelo, Francisco; Carrilho, Francisco; Barros, Luisa; Batista, Carla; Melo, Miguel; Ferreira, Manuel MIntrodução: A diabetes mellitus apresenta diferentes complicações micro e macrovasculares, sendo também um fator de risco para diversas complicações orais. O objetivo do presente estudo é estabelecer uma relação entre a cárie dentária em doentes com diabetes mellitus do tipo 1 tratados com múltiplas injeções de insulina e em indivíduos sem diabetes. É ainda objetivo caracterizar os hábitos de higiene oral desta...
Selenium and Thyroid Disease: From Pathophysiology to Treatment
Ventura, Mara; Melo, Miguel; Carrilho, FranciscoIntroduction. Selenium is a micronutrient embedded in several proteins. In adults, the thyroid is the organ with the highest amount of selenium per gram of tissue. Selenium levels in the body depend on the characteristics of the population and its diet, geographic area, and soil composition. In the thyroid, selenium is required for the antioxidant function and for the metabolism of thyroid hormones. Methods. We...