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Coronary intravascular lithotripsy effectiveness and safety in a real-world cohort

Oliveira, Catarina; Vilela, Marta; Menezes, Miguel Nobre; Silva Marques, João; Jorge, Claudia; Rodrigues, Tiago; Almeida Duarte, José

Background: Coronary artery calcification is a predictor of adverse outcomes after percutaneous coronary intervention (PCI). Intravascular lithotripsy (IVL) is a promising tool for the treatment of calcified lesions. The aim of this study was to assess the effectiveness and safety of IVL. Methods: A single-center observational study of PCI procedure, with assessment of the outcomes of patients undergoing PCI us...


Management of coronary artery disease in patients undergoing transcatheter aort...

Tarantini, Giuseppe; Tang, Gilbert; Nai Fovino, Luca; Blackman, Daniel; Van Mieghem, Nicolas M.; Kim, Won-Keun; Karam, Nicole; Carrilho-Ferreira, Pedro

Significant coronary artery disease (CAD) is a frequent finding in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI), and the management of these two conditions becomes of particular importance with the extension of the procedure to younger and lower-risk patients. Yet, the preprocedural diagnostic evaluation and the indications for treatment of significant CAD in TA...


Transcatheter interventions for left-sided valvular heart disease complicated b...

Fraccaro, Chiara; Karam, Nicole; Möllmann, Helge; Bleiziffer, Sabine; Bonaros, Nikolaos; Teles, Rui Campante; Carrilho-Ferreira, Pedro; Chieffo, Alaide

Valvular heart disease (VHD) is one of the most frequent causes of heart failure (HF) and is associated with poor prognosis, particularly among patients with conservative management. The development and improvement of catheter-based VHD interventions have broadened the indications for transcatheter valve interventions from inoperable/high-risk patients to younger/lower-risk patients. Cardiogenic shock (CS) asso...


Clinical correlates and prognostic impact of neurologic disorders in Takotsubo ...

Cammann, Victoria L.; Scheitz, Jan F.; von Rennenberg, Regina; Jäncke, Lutz; Nolte, Christian H.; Szawan, Konrad A.; Stengl, Helena; Würdinger, Michael

Cardiac alterations are frequently observed after acute neurological disorders. Takotsubo syndrome (TTS) represents an acute heart failure syndrome and is increasingly recognized as part of the spectrum of cardiac complications observed after neurological disorders. A systematic investigation of TTS patients with neurological disorders has not been conducted yet. The aim of the study was to expand insights rega...


Impact of atrial fibrillation on outcome in Takotsubo syndrome: data from the I...

El‐Battrawy, Ibrahim; Cammann, Victoria L.; Kato, Ken; Szawan, Konrad A.; Di Vece, Davide; Rossi, Aurelio; Wischnewsky, Manfred; Hermes‐Laufer, Julia

Background Atrial fibrillation (AF) is a major risk factor for mortality. The prevalence, clinical correlates, and prognostic impact of AF in Takotsubo syndrome (TTS) have not yet been investigated in a large patient cohort. This study aimed to investigate the prevalence, clinical correlates, and prognostic impact of AF in patients with TTS. Methods and Results Patients with TTS were enrolled from the Internati...


Ethnic comparison in takotsubo syndrome : novel insights from the International...

Imori, Yoichi; Kato, Ken; Cammann, Victoria L.; Szawan, Konrad A.; Wischnewsky, Manfred; Dreiding, Sara; Würdinger, Michael; Schönberger, Maximilian

Background: Ethnic disparities have been reported in cardiovascular disease. However, ethnic disparities in takotsubo syndrome (TTS) remain elusive. This study assessed differences in clinical characteristics between Japanese and European TTS patients and determined the impact of ethnicity on in-hospital outcomes. Methods: TTS patients in Japan were enrolled from 10 hospitals and TTS patients in Europe were enr...


Prognostic impact of acute pulmonary triggers in patients with Takotsubo syndro...

Kato, Ken; Cammann, Victoria L.; Napp, L. Christian; Szawan, Konrad A.; Micek, Jozef; Dreiding, Sara; Levinson, Rena A.; Petkova, Vanya

Aims: Acute pulmonary disorders are known physical triggers of takotsubo syndrome (TTS). This study aimed to investigate prevalence of acute pulmonary triggers in patients with TTS and their impact on outcomes. Methods and results: Patients with TTS were enrolled from the International Takotsubo Registry and screened for triggering factors and comorbidities. Patients were categorized into three groups (acute pu...


The CTo-aBCDE score : a new predictor of success in chronic total occlusions

Rigueira, Joana; Aguiar-Ricardo, Inês; Menezes, Miguel Nobre; Santos, Rafael; Rodrigues, Tiago; Cunha, Nelson; Francisco, Ana Rita

Introduction: Patient selection for percutaneous coronary intervention (PCI) in chronic total occlusions (CTOs) is crucial to procedural success. Our aim was to identify independent predictors of success in CTO PCI in order to create an accurate score. Methods: In a single-center observational registry of CTO PCI, demographic and clinical data and anatomical characteristics of coronary lesions were recorded. Li...


One stent versus two stents for distal LM PCI: insights from the experience of ...

Santos, R.; Menezes, Miguel Nobre; Carrilho-Ferreira, Pedro; Calhaz-Jorge, Carlos; Francisco, A. R.; Oliveira, Eduardo Infante de; Duarte, J.

Distal left main (LM) PCIremains a challenge. One of the most debated issues is whether to use a single vs 2 stent provisional strategy. While most studies and guidelines favour a single stent strategy, the recent DK-CRUSH V trial has shown better results with a 2 stent strategy.


Coexistence and outcome of coronary artery disease in Takotsubo syndrome

Templin, Christian; Ghadri, Jelena R; Ruschitzka, Frank; Lüscher, Thomas F; Braunwald, Eugene; Bauersachs, Johann; Bax, Jeroen J; Münzel, Thomas

Aims: Takotsubo syndrome (TTS) is an acute heart failure syndrome, which shares many features with acute coronary syndrome (ACS). Although TTS was initially described with angiographically normal coronary arteries, smaller studies recently indicated a potential coexistence of coronary artery disease (CAD) in TTS patients. This study aimed to determine the coexistence, features, and prognostic role of CAD in a l...


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