3 documents found, page 1 of 1
Can sexual transmission support the enzootic cycle of Trypanosoma cruzi?
Rios, Adriano; Ribeiro, Marcelle; Sousa, Alessandro; Pimentel, Fernando; Hagström, Luciana; Andrade, Rafael; Alves, Rozeneide M.; Rosa, Ana de CássiaBACKGROUND Trypanosoma cruzi circulates in sylvatic habitats, mainly through blood-feeding triatomines, although other routes also contribute to its dispersion. Sexual transmission of T. cruzi is an understudied topic, especially among wild mammals. Because of the difficulties inherent to field work, experimentally infected mice are frequently used to evaluate the transmission of T. cruzi. OBJECTIVE This study ...
Trypanosoma cruzi in the chicken model : Chagas-like heart disease in the absen...
Teixeira, Antonio Raimundo Lima Cruz; Gomes, Clever; Nitz, Nadjar; Sousa, Alessandro O.; Alves, Rozeneide M.; Guimaro, Maria C.; Cordeiro, CiroBackground: The administration of anti-trypanosome nitroderivatives curtails Trypanosoma cruzi infection in Chagas disease patients, but does not prevent destructive lesions in the heart. This observation suggests that an effective treatment for the disease requires understanding its pathogenesis. Methodology/Principal Findings: To understand the origin of clinical manifestations of the heart disease we used a ...
Sexual transmission of American trypanosomiasis in humans : a new potential pan...
Araújo, Perla Fabíola de; Almeida, Adriana B.; Pimentel, Carlos F.; Silva, Adriano R.; Sousa, Alessandro; Valente, Sebastião A.; Valente, Vera C.Background: the Trypanosoma cruzi infection endemic in Latin America has now spread to several countries across four continents; this endemic involves triatomine vector-free protists. We hypothesised that the sexual transmission of T. cruzi contributes to the ongoing spread of Chagas disease. Objectives: a short-term longitudinal study was conducted to evaluate this hypothesis. Methods: the study population com...