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Unraveling the Nanoscopic Organization and Function of Central Mammalian Presyn...

Carvalhais, Lia G.; Martinho, Vera C.; Ferreiro, Elisabete; Pinheiro, Paulo S.

The complex, nanoscopic scale of neuronal function, taking place at dendritic spines, axon terminals, and other minuscule structures, cannot be adequately resolved using standard, diffraction-limited imaging techniques. The last couple of decades saw a rapid evolution of imaging methods that overcome the diffraction limit imposed by Abbe's principle. These techniques, including structured illumination microscop...


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