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Liposomal Delivery of Newly Identified Prophage Lysins in a Pseudomonas aerugin...

Morais, Diana; Tanoeiro, Luis; Marques, Andreia T.; Gonçalves, Tiago; Duarte, Aida; Matos, António Pedro Alves; Vital, Joana S.

Pseudomonas aeruginosa is a Gram-negative opportunistic bacterium that presents resistance to several antibiotics, thus, representing a major threat to human and animal health. Phage-derived products, namely lysins, or peptidoglycan-hydrolyzing enzymes, can be an effective weapon against antibiotic-resistant bacteria. Whereas in Gram-positive bacteria, lysis from without is facilitated by the exposed peptidogly...


Liposomal Delivery of Newly Identified Prophage Lysins in a Pseudomonas aerugin...

Morais, Diana; Tanoeiro, Luís; Marques, Andreia; Gonçalves, Tiago; Duarte, A.; Matos, António; Vital, Joana; Cruz, Maria Eugénia Meirinhos

Pseudomonas aeruginosa is a Gram-negative opportunistic bacterium that presents resistance to several antibiotics, thus, representing a major threat to human and animal health. Phage-derived products, namely lysins, or peptidoglycan-hydrolyzing enzymes, can be an effective weapon against antibiotic-resistant bacteria. Whereas in Gram-positive bacteria, lysis from without is facilitated by the exposed peptidogly...


Liposomal delivery of newly identified prophage lysins in a Pseudomonas aerugin...

Morais, Diana; Tanoeiro, Luís; Marques, Andreia T.; Gonçalves, Tiago; Duarte, Aida; Matos, António Pedro Alves; Vital, Joana S.

Pseudomonas aeruginosa is a Gram-negative opportunistic bacterium that presents resistance to several antibiotics, thus, representing a major threat to human and animal health. Phage-derived products, namely lysins, or peptidoglycan-hydrolyzing enzymes, can be an effective weapon against antibiotic-resistant bacteria. Whereas in Gram-positive bacteria, lysis from without is facilitated by the exposed peptidogly...


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