34 documents found, page 1 of 4
Natural killer activity in a medium-term multi-organ bioassay for carcinogenesis
Tozzi Spinardi, Ana Lúcia [UNESP]; Kaneno, Ramon [UNESP]; Marchesan Rodrigues, Maria Aparecida [UNESP]; Fávero Salvadori, Daisy Maria [UNESP]Made available in DSpace on 2022-04-28T19:56:11Z (GMT). No. of bitstreams: 0 Previous issue date: 1999-01-01; Natural killer (NK) cell activity was evaluated after the initiation and promotion steps in a medium-term multi-organ bioassay for carcinogenesis. NK cell activity was assessed in vitro by Cr51 release assay at the 4th and 30th weeks of the experiment. Male Wistar rats were sequentially initiated with N...
Cell-mediated immunity and expression of MHC class I and class II molecules in ...
do Prado Duzanski, Anderson [UNESP]; Flórez, Luis Mauricio Montoya [UNESP]; Fêo, Haline Ballestero [UNESP]; Romagnoli, Graziela Gorete [UNESP]Made available in DSpace on 2022-04-29T08:40:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-07-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The canine transmissible venereal tumor (CTVT) is a transplantable cancer with the ability evade the immune system, despite strict immune surveillance of the host; i...
Cytotoxic Activity and Lymphocyte Subtypes in Mice Selected for Maximal and Min...
Castoldi, Lindsey; Romagnoli, Graziela Gorete [UNESP]; De Assis Golim, Marjorie [UNESP]; Ribeiro, Orlando Garcia; Martinez Ibañez, Olga CéliaMade available in DSpace on 2022-04-29T08:40:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01; AIRmax and AIRmin mice strains were selected according to the intensity of their acute inflammatory responsiveness. Previous studies have shown that AIR mice differ in their resistance to chemically induced skin tumors and in the development of melanoma metastases, in addition to differences in neutroph...
ST2/IL-33 signaling promotes malignant development of experimental squamous cel...
Amôr, Nádia Ghinelli; de Oliveira, Carine Ervolino; Gasparoto, Thaís Helena; Boas, Vanessa Garcia Vilas; Perri, Graziela; Kaneno, Ramon [UNESP]Made available in DSpace on 2022-04-29T08:27:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-07-20; Squamous cell carcinoma (SCC) is the second most common form of skin cancer and the mechanism(s) involved in the progression of this tumor are unknown. Increases in the expression of IL-33/ST2 axis components have been demonstrated to contribute to neoplastic transformation in several tumor models and i...
Natural products from cyanobacteria with antimicrobial and antitumor activity
Silva-Stenico, Maria Estela; Kaneno, Ramon [UNESP]; Zambuzi, Fabiana Albani [UNESP]; Vaz, Marcelo G.M.V.; Alvarenga, Danillo O.; Fiore, Marli FátimaMade available in DSpace on 2022-04-29T07:13:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-01-01; Cyanobacteria are an important source of structurally bioactive metabolites, with cytotoxic, antiviral, anticancer, antimitotic, antimicrobial, specific enzyme inhibition and immunosuppressive activities. This study focused on the antitumor and antimicrobial activities of intra and extracellular cyanoba...
Physical, functional and biochemical features of Nanoskin® bacterial cellulose ...
Viveiros, Magda Massae Hata [UNESP]; Rainho, Cláudia Aparecida [UNESP]; Ramirez, Jofer Andree Zamame [UNESP]; Kaneno, Ramon [UNESP]Made available in DSpace on 2022-05-01T09:47:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-02-01; We evaluated the feasibility of Nanoskin®, a bacterial cellulose (BC) nanofiber membrane, as a potential scaffold for cell transference therapy. Nanoskin® does not induce lymphocyte proliferation, but it does not kill lymphocytes. Human mesenchymal stem cells (MSCs) and lymphocytes produced significantl...
Minimum effective concentration of paclitaxel improves the effectivity of dendr...
Camargo, Marcela Rodrigues [UNESP]; Rodrigues, Cecilia Pessoa [UNESP]; Gorgulho, Carolina Mendonca [UNESP]; Zambuzi, Fabiana Albani [UNESP]Made available in DSpace on 2020-12-10T22:01:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-01-01; Univ Estadual Paulista UNESP, Botucatu, SP, Brazil; Fundacao Amaral Carvalho, Jau, Brazil; Univ Estadual Paulista UNESP, Botucatu, SP, Brazil
Anti-PSMA monoclonal antibody increases the toxicity of paclitaxel carried by c...
Comparetti, Edson José [UNESP]; Romagnoli, Graziela Gorete [UNESP]; Gorgulho, Carolina Mendonça [UNESP]; Pedrosa, Valber de Albuquerque [UNESP]Made available in DSpace on 2020-12-12T02:14:17Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-11-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Multiple-wall carbon nanotubes (CNTs) were functionalized with polyethyleneimine in order to incorporate paclitaxel (PTX), the first line chemotherapeutic agent for prosta...
Anti-EGFR-coated gold nanoparticles in vitro carry 5-fluorouracil to colorectal...
Liszbinski, Raquel B. [UNESP]; Romagnoli, Graziela G. [UNESP]; Gorgulho, Carolina M. [UNESP]; Basso, Caroline R. [UNESP]; Pedrosa, Valber A. [UNESP]Made available in DSpace on 2020-12-12T01:57:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; The aim of the current study is to present a strategy to improve the effciency of 5-fluorouracil (5-FU), which is widely used as antineoplastic agent against solid tumors-based on the use of gold nanocarriers to overcome the resistance of colorectal cancer cells. 5-FU was loaded on gold nanoparticles (A...
Blocking drug-induced autophagy with chloroquine in HCT-116 colon cancer cells ...
Zamame Ramirez, Jofer Andree [UNESP]; Romagnoli, Graziela Gorete [UNESP]; Falasco, Bianca Francisco [UNESP]; Gorgulho, Carolina Mendonça [UNESP]Made available in DSpace on 2020-12-12T02:01:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-07-01; Higher College of Technology; Autophagy is an important mechanism for tumor escape, allowing tumor cells to recover from the damage induced by chemotherapy, radiation therapy, and immunotherapy and contributing to the development of resistance. The pharmacological inhibition of autophagy contributes to ...