85 documents found, page 1 of 9
Experimental validation of time-explicit ultrasound propagation models with sou...
Fernandes, Nuno Alexandre Tavares Campos; Sharma, Shivam; Arieira, Ana Filipa Amorim; Hinckel, Betina; Silva, Filipe SamuelUltrasonic wave attenuation in biological tissues arises from complex interactions between mechanical, structural, and fluidic properties, making it essential to identify dominant mechanisms for accurate simulation and device design. This work introduces a novel integration of experimentally measured tissue parameters into time-explicit nonlinear acoustic wave simulations, in which the equations are directly so...
Development of a hydrophone for measuring the propagation of acoustic waves in ...
Pereira, Anabela; Cardoso, Vanessa Fernandes; Martins, Marcos Silva; Fernandes, Nuno Alexandre Tavares Campos; Carvalho, Óscar Samuel NovaisIn the past years, the prevalence of neurodegenerative diseases has in-creased, highlighting the urgent need to better understand and combat these diseases. Innovative ultrasound treatments have shown promising results but require further investigation, particularly regarding the pene-tration of acoustic waves into the brain. This work focus on developing a hydrophone to study acoustic wave penetration in biolo...
Models for light propagation in the head: trends and implementation of Finite E...
Fernandes, Filipa Gracinda Silva; Silva, Filipe Samuel; Sousa, Nuno; Carvalho, Óscar Samuel Novais; Catarino, Susana OliveiraThe simulation of light propagation in the head tissues has become of interest due to its applicability in transcranial photobiomodulation (tPBM). In silico studies appear as an effective way to research tPBM dosimetry and understand the light reach in the head tissues, as well as potential issues regarding tissue heating. Nonetheless, these computer models are still very simple and come with several limitation...
Unraveling the potential of transcranial photobiomodulation and ultrasound stim...
Fernandes, Nuno Alexandre Tavares Campos; Catarino, Susana Oliveira; Carvalho, Óscar Samuel NovaisThe human brain is the most sophisticated and the finest processing unit ever designed, but mental and neurological disorders are an imminent threat to its functioning. Indeed, brain disorders comprise one of the most challenging health issues of modern society due to their tremendous health, social, and economic impact. However, pharmacological therapies face a physical obstacle – the blood-brain barrier (BBB)...
Mapping and modeling ultrasound propagation for tailored brain therapies
Carvalho, Óscar Samuel NovaisThe work presented here is dedicated to the mapping and modeling of the transmission profiles of optical and mechanical stimuli in the brain, with the ultimate goal of optimizing transcranial stimulation techniques for the treatment of neurological and psychiatric disorders. The presentation highlights the methodology used for acoustic transmission studies in brain tissues. A specialized device was developed fo...
Experimental and in silico models for studying light propagation in the head
Fernandes, Filipa Gracinda Silva; Silva, Filipe Samuel; Sousa, Nuno; Carvalho, Óscar Samuel Novais; Catarino, Susana OliveiraTranscranial photobiomodulation (tPBM) is an alternative therapy to conventional approaches, with clinical studies that show promising results for the treatment of several neurological pathologies, such as stroke and dementia related conditions. Despite its potential, the optimal light parameters and dosimetry for effective tPBM therapy remain uncertain, with most literature on this topic highlighting the need ...
Green vibrations: dynamic stiffness and constitutive modelling of recycled nonw...
Fernandes, Nuno Alexandre Tavares Campos; Alves, Diana Isabel Sousa; Ruivo, Francisco; Ferreira, Diana P.; Carvalho, Óscar Samuel NovaisThe increasing concern over environmental sustainability has driven the exploration of waste-based materials as innovative engineering applications. Dynamic compressive mechanical tests were performed at varying frequencies to evaluate energy dissipation and stiffness. The results show that compressed samples exhibit higher Young's modulus, tensile strength, and dynamic stiffness compared to their uncompressed ...
Bacterial nanocellulose as a versatile scaffold for biomedical applications: sy...
Melro, Liliana Sofia Silva Ferreira Pinto; Alves, Cátia Sofia Pereira; Fernandes, Marta Susana Machado; Rocha, Sofia Gomes; Mehravani, BehnazBacterial nanocellulose (BNC) consists of nanofibres of cellulose randomly entangled during their synthesis by particular bacterium cells during fermentation. Thus, it may be regarded as a unique three-dimensional of pure cellulose that is consolidated during the generation of the fibres by their microbiological factories. The metabolic synthesis and purification processes are approached, underscoring its poten...
Biomechanical and clinical effects of spinal traction: enhancing lumbar health ...
Arieira, Ana Filipa Amorim; Fernandes, Nuno; Fernandes, Pedro; Silva, Filipe Samuel; Carvalho, Óscar Samuel Novais; Leal, Ana Isabel Neto CardosoIntroduction: Lumbar disc degeneration (DD), one of the leading causes of disability worldwide, disrupts spinal biomechanics, leading to pain, disability, and reduced quality of life. Low back pain (LBP) affects up to 80% of the global population [1]. This degeneration process reduces disc height, alters load distribution, and contributes to herniation and nerve impingement [2]. Spinal traction, a non-invasive ...
Unlocking the secrets of knee joint unloading: a systematic review and biomecha...
Fernandes, Nuno Alexandre Tavares Campos; Arieira, Ana Filipa Amorim; Hinckel, Betina; Silva, Filipe Samuel; Carvalho, Óscar Samuel NovaisBackground/Objectives: This review analyzes the effects of invasive and non-invasive methods of knee joint unloading on knee loading, employing a biomechanical model to evaluate their impact. Methods: PubMed, Web of Science, Cochrane, and Scopus were searched up to 15 May 2024 to identify eligible clinical studies evaluating Joint Space Width, Cartilage Thickness, the Western Ontario and McMaster Universities O...