3 documents found, page 1 of 1
Estudo do mecanismo de ação da atividade antinociceptiva da Riparina II de Anib...
Carvalho, Alyne Mara Rodrigues deThe unripe fruit of the species of Aniba riparia (Nees) Mez, found some alkamides, one in particular, Riparin II (RipII) has an interesting therapeutic potential. Previous studies showed that it had anxiolytic and antidepressant effects as well as an antiinflammatory effect. This study was conducted after approval by the CEUA/UFC (n° 41/15). The aim of the study was to evaluate the role of RipII in nociception ...
Evaluation of the anti-inflammatory activity of riparin II (O-methil- N-2-hidro...
Carvalho, Alyne Mara Rodrigues de; Rocha, Nayrton Flávio Moura; Vasconcelos, Leonardo Freire; Rios, Emiliano Ricardo Vasconcelos; Dias, Marília LeiteRiparin II (RipII), an alkamide isolated from the green fruit of Aniba riparia, was tested in the various animal models of inflammation to investigate its anti-inflammatory activity. Male Wistar rats (180–240 g) were treated with RipII by gavage at doses 25 or 50 mg/kg, before initiating the inflammatory responses. The tests used were paw edema induced by carrageenan, dextran, histamine or serotonin; peritoniti...
Estudo da atividade antinociceptiva e antiinflamatória da riparina II (O-metil-...
Carvalho, Alyne Mara Rodrigues deRiparin II, an alcamide isolated from the green fruit of Aniba riparia, was tested in animal models, such as acetic acid-induced abdominal writhing, formalin test, hot plate test, capsaicin and glutamate-induced nociception, paw edema induced by carrageenan, dextran, histamine and serotonin and peritonitis induced by carrageenan and fMLP, in order to evaluate its antinociceptive and antiinflamatory activities. ...