100 documents found, page 1 of 10
Valorisation of protein-rich extracts from spent brewer’s yeast (Saccharomyces ...
Oliveira, Ana Sofia; Ferreira, Carlos; Pereira, Joana Odila; Pintado, Manuela E.; Carvalho, Ana P.As one of the main brewing by-products, Saccharomyces cerevisiae extracts (from spent yeast) have been commercialized as food supplement for years. Among their several claims, the application as protein source is highlighted. In fact, their high protein content (about 45–60%) including essential amino acids with high biological value, safety and low cost are primarily responsible for their spreading in agri-foo...
Candida albicans: the current status regarding vaginal infections
Faustino, Margarida; Ferreira, Carlos M. H.; Pereira, Ana Margarida; Carvalho, Ana P.Vaginal infections caused by Candida albicans are a significant global health concern due to their recurrence and negative impact on quality of life. This review examines the pathogenesis of C. albicans infections, emphasizing critical virulence factors such as biofilm formation, adherence, and phenotypic switching. Risk factors include immune system suppression, antibiotic use, and hormonal changes, all of whi...
Zeolite modification for optimizing Fenton reaction in methylene blue dye degra...
Carvalho, Ana P.; Costa, José; Martins, Angela; Fonseca, António; Neves, Isabel C.; Nunes, NelsonTextile dyes often prove resistant to conventional wastewater treatment processes because of their complex molecular structures. Advanced oxidation methods, such as the Fenton reaction, have thus been recognized as a promising approach for environmental remediation by decomposing these pollutants. This work aimed to study the efficacy of modified zeolites as catalysts in the Fenton reaction for dye degradation,...
Purification of bioactive peptides from spent yeast autolysates
Oliveira, Ana Sofia; Pereira, Ana Margarida; Ferreira, Carlos M.H.; Pereira, Joana Odila; Amorim, Manuela; Faustino, Margarida; Durão, JoanaSpent brewer’s yeast have been described as an important source for bioactive peptides, with their properties well proven over the years. Besides the brewing sector, growing of large-scale processes on synthetic biology industry has generated a substantial amount of spent engineered yeast with further potential to be valued in a circular economy approach. In line with this perception, in this work, peptide-rich...
Up-scalable approaches for yeast mannan oligosaccharides (MOS) production: char...
Faustino, Margarida; Durão, Joana; Pereira, Carla F.; Pereira, Ana Margarida; Oliveira, Ana Sofia; Sousa, Sérgio; Ribeiro, Alessandra BragaMannan oligosaccharides (MOS) are widely used as feed additives due to their effects on gut microbiome modulation. Its application in the nutraceutical and functional food industries is also increasing. Numerous studies portraying MOS production from β-mannans can be found, but its production from yeast mannans is barely explored. Herein, two up-scalable approaches to produce yeast-derived MOS are presented: hy...
Vaginal prevention of Candida albicans: synergistic effect of lactobacilli and ...
Faustino, Margarida; Pereira, Joana Odila; Pereira, Ana Margarida; Oliveira, Ana Sofia; Ferreira, Carlos M. H.; Pereira, Carla F.; Durão, JoanaVulvovaginal candidiasis (VVC) affects approximately 30-50% of women at least once during their lifetime, causing uncomfortable symptoms and limitations in their daily quality of life. Antifungal therapy is not very effective, does not prevent recurrencies and usually causes side effects. Therefore, alternative therapies are urgently needed. The goal of this work was to investigate the potential benefits of usi...
Use of various sugarcane byproducts to produce lipid extracts with bioactive pr...
Pereira, Joana Odila; Oliveira, Diana; Faustino, Margarida; Vidigal, Susana S. M. P.; Pereira, Ana Margarida; Ferreira, Carlos M. H.Sugarcane, a globally cultivated crop constituting nearly 80% of total sugar production, yields residues from harvesting and sugar production known for their renewable bioactive compounds with health-promoting properties. Despite previous studies, the intricate interplay of extracts from diverse sugarcane byproducts and their biological attributes remains underexplored. This study focused on extracting the lipi...
An eco-friendly and up-scalable approach to extract canthaxanthin from yeast cells
Pereira, Ana M.; Durão, Joana; Pereira, Joana Odila; Ferreira, Carlos; Faustino, Margarida; Oliveira, Ana Sofia; Pereira, Carla F.; Pintado, Manuela E.Canthaxanthin is a naturally occurring ketocarotenoid pigment present in plants, algae, bacteria and some fungi. In addition to its coloring role, canthaxanthin has an excellent antioxidant activity, thus having additional market demands in the feed, food, cosmetic and pharmaceutical industries. Canthaxanthin can be directly isolated from its natural source or produced by chemical synthesis, but these strategie...
Hierarchical zeolites prepared Using a surfactant-mediated strategy: ZSM-5 vs. ...
Martins, Angela; Amaro, Beatriz; Santos, M. Soledade C. S.; Nunes, Nelson; Elvas Leitao, Ruben; Carvalho, Ana P.Hierarchical ZSM5 and Y zeolites were prepared through a surfactant-mediated strategy with NH4OH changing the duration of the treatment and the amount of CTAB surfactant and taking as reference multiples of the critical micellar concentration (CMC). The materials were characterized using powder X-ray diffraction, N2 adsorption isotherms at -196 degrees C, and SEM and TEM microscopy. The catalytic performance wa...
Defatted nannochloropsis oculata biomass: waste or resource?
Sousa, Sérgio; Machado, Manuela; Coscueta, Ezequiel; Ferreira, Andreia S.; Nunes, Cláudia; Coimbra, Manuel A.; Freitas, Ana C.; Carvalho, Ana P.Microalgae are recognized as a valuable source of a panoply of compounds. In addition to the extensively investigated lipid fraction comprising polyunsaturated fatty acids (PUFA), microalgae biomass also encompasses other compounds with potentially relevant biological activities. This work innovatively repurposes the defatted biomass (DB) of Nannochloropsis oculata, highlighting its potential value beyond the l...