Objetivos: Caracterizar o impacto da atual pandemia de COVID-19 na ansiedade, medo e stress nos profissionais de saude oral. Metodos: Utilizou-se um questionario autoaplicado online que foi enviado, via email, para tres associacoes na area da Medicina Dentaria. As variaveis categoricas foram descritas atraves de frequencias absolutas e relativas. As variaveis continuas foram descritas utilizando a media e o des...
Objetivos: Caracterizar os conhecimentos e atitudes dos professores portugueses e timorenses da Educação Pré-Escolar e dos 1.º e 2.º ciclos que lecionam em Timor-Leste em relação à saúde oral das crianças e seus determinantes. Métodos: Neste estudo do tipo transversal, foi aplicado um questionário autoaplicado online para a recolha de dados. Foram convidados a participar neste estudo 13 escolas e 149 professore...
Dismal prognosis of glioblastoma (GBM) prompts for the identification of response predictors and therapeutic resistance mechanisms of current therapies. The authors investigated the impact of c-Met, HGF, VEGFR2 expression and microvessel density (MVD) in GBM patients submitted to second-line chemotherapy with bevacizumab. Immunohistochemical expression of c-Met, HGF, VEGFR2, and MVD was assessed in tumor specim...
The deficiency of 21-hydroxylase due to CYP21A2 pathogenic variants is a rather frequent disease with serious consequences, going from a real mortality risk to infertility and to milder symptoms, nevertheless important for affecting the patients’ self-esteem. In the most severe cases life-threatening adrenal salt wasting crises may occur. Significant morbidity including the possibility of mistaken gender determ...
Objectivo: Estudar a evolução dos parâmetros quantitativos e qualitativos obtidos na tomografia de coerência óptica spectral domain (SD-OCT) num sub-grupo de doentes com degeneração macular da idade (DMI) sujeitos a injecções intravítreas (IV) de bevacizumab. Procurou-se também verificar se estes parâmetros poderão funcionar como factores de prognóstico da acuidade visual (AV) pós- terapêutica com IV de bevaciz...
Purpose The prognosis of gastric cancer (GC) is poor, and the molecular pathogenesis players are vastly unknown. Surgery remains the primary option in GC treatment. The aim of this study was to investigate the impact of somatic CDH1 alterations in prognosis and survival of patients with GC. Patients and Methods A series of patients with sporadic and familial GC (diffuse and intestinal; n _ 246) were analyzed fo...
Background. Data on human immunodeficiency virus (HIV) infected patients receiving dialysis in Portugal is scarce. Methods. This nationwide epidemiological survey retrospectively evaluates HIV-infected patients on chronic dialysis in Portugal between 1997 and 2002. Results. Sixty-six patients were evaluated (mean age: 39.1±1.6 years, 47 men, 35 black African). Sixty-two patients started dialysis and 4 patients ...
Background: Data on human immunodeficiency virus (HIV) infected patients receiving dialysis in Portugal is scarce. Methods: This nationwide epidemiological survey retrospectively evaluates HIV-infected patients on chronic dialysis in Portugal between 1997 and 2002. Results: Sixty-six patients were evaluated (mean age: 39.1±1.6 years, 47 men, 35 black African). Sixty-two patients started dialysis and 4 patients ...