Introduction: The assessment of body temperature requires that care professionals, in their decision-making, determine the method of assessment with scientific and technical rigor. Therefore, the goals of this study are to determine the reliability of five methods for assessing body temperature in critically ill patients and determine the accuracy of four non-invasive temperature assessment methods compared to ...
Glioblastoma multiforme (GBM) is the most common, aggressive, and fatal primary malignant brain tumor in adults. The therapeutic efficacy of temozolomide (TMZ) is limited owing to frequent treatment resistance. The latter is in part related to the overexpression of redox systems such as the thioredoxin system. This system is fundamental for cell survival and proliferation, regulating hypoxia inducible factor-1a...
This empirical study is based on the author’s PhD thesis. It aims at rescuing from the Sands of Time the spirit of the destination under analysis, basing itself on the data collected from 1930s newspapers, besides contemporary approaches to that decade in the fields of Political History, War, Tourism, and Leisure. In 1910 the Figueiredos were led to Estoris due to the microclimate, and by 1914 the entrepreneur ...
Set in the Atlantic outskirts of Lisbon, Estoril was for centuries renowned for the thermal springs whose waters were linked to the 12th-century legend of a horse whose vitality was regained after bathing in them. The blessed liquid was chemically studied from the mid-1700s on and experimented by King Joseph I. The prestigious royal presence and Estoril’s coastal setting justified the growth of attendants acros...
Consumo de pescado em Portugal, Riscos e beneficios do consumo de pescado, Metilmercúrio (MeHg), População mais suscetível ao MeHg, Avaliação da exposição ao MeHg, Recomendações para o consumo de pescado.
This article presents itself as an excerpt from the institutional research of the Group on Education, Museum, Culture and Childhood (GEPEMCI), aimed at investigating the relationship between children from zero to six years old with museums and cultural centers in the city of Rio de Janeiro. The main objective is to encourage reflections on the presence of babies and their families in museums and cultural spaces...
Selenium (Se) is a micronutrient with essential physiological functions achieved through the production of selenoproteins. Adequate Se intake has health benefits and reduces mercury (Hg) toxicity, which is important due to its neurotoxicity. This study determined the Se status and redox enzyme, including selenoproteins’, activity in pregnant women highly exposed to Hg (between 1 to 54 µg Hg/L blood) via fish co...
Glioblastoma multiforme (GBM) is the most aggressive and common form of glioma. GBM, like many other tumors, expresses high levels of redox proteins, such as thioredoxin (Trx) and thioredoxin reductase (TrxR), allowing tumor cells to cope with high levels of reactive oxygen species (ROS) and resist chemotherapy and radiotherapy. Thus, tackling the activity of these enzymes is a strategy to reduce cell viability...
Glioblastoma multiforme (GBM) is the most aggressive and common form of glioma. GBM, like many other tumors, expresses high levels of redox proteins, such as thioredoxin (Trx) and thioredoxin reductase (TrxR), allowing tumor cells to cope with high levels of reactive oxygen species (ROS) and resist chemotherapy and radiotherapy. Thus, tackling the activity of these enzymes is a strategy to reduce cell viability...
Selenium (Se) is a micronutrient with essential physiological functions achieved through the production of selenoproteins. Adequate Se intake has health benefits and reduces mercury (Hg) toxicity, which is important due to its neurotoxicity. This study determined the Se status and redox enzyme, including selenoproteins’, activity in pregnant women highly exposed to Hg (between 1 to 54 µg Hg/L blood) via fish co...