111 documents found, page 1 of 12

Cardiopulmonary, Metabolic and Perceived Exertion Characteristics Among Portugu...

Background: Firefighting is a strenuous occupation that requires firefighters to be in excellent physical condition. However, some of these professionals are not sufficiently physically fit for duty, negatively impacting their performance. Objective: To cardiopulmonary characterize Portuguese firefighters at different exercise intensities to clarify if their physical fitness profile is adequate to overcome thei...

Transmural Remission Improves Clinical Outcomes Up to 5 years in Crohn's Disease

Introduction: Evidence supporting transmural remission (TR) as a long-term treatment target in Crohn's disease (CD) is still unavailable. Less stringent but more reachable targets such as isolated endoscopic (IER) or radiologic remission (IRR) may also be acceptable options in the long-term. Methods: Multicenter retrospective study including 404 CD patients evaluated by magnetic resonance enterography and colon...

Epidemiological, Social and Economic Burden of Severe Hypoglycaemia in Patients...

Introduction: The aim of this review was to identify and review studies reporting on the epidemiological, social and economic impact associated with severe hypoglycaemia (SH) in people with diabetes mellitus (DM) in Portugal. Methods: A structured literature search was carried out in PubMed and Embase using a predefined selection criterion. Studies published in either Portuguese or English, between January 2010...

High Incidence of Early Thalamic Lesions in the Continuous Spike-Wave Related w...

Objective: Continuous Spike-Wave during slow Sleep (CSWS) syndrome associates a clinically important neurocognitive regression with strong activation of non-REM sleep spikes. Its mechanisms remain unknown, but a contribution of rare perinatal thalamic injuries has been highlighted. We determine the incidence of such lesions in a cohort of CSWS patients. Methods: N = 65 patients with CSWS and a control group (N ...

Incidental versus symptomatic nonfunctioning pituitary adenomas: Are they diffe...

Background Nonfunctioning pituitary adenomas (NFPAs) constitute one of the most common tumours in the sellar region and are often discovered only when associated with compressive symptoms. With the frequent use of brain imaging, there has been an increase in the prevalence of incidentally discovered NFPAs.Aim We aim to determine the prevalence of incidental diagnosis with NPAs observed over a decade and compare...

Invasive and Subcutaneous Infections Caused by Filamentous Fungi: Report from a...

Invasive fungal infections (IFI) have significantly increased over the past years due to advances in medical care for the at-risk immunocompromised population. IFI are often difficult to diagnose and manage, and can be associated with substantial morbidity and mortality. This study aims to contribute to understanding the etiology of invasive and subcutaneous fungal infections, their associated risk factors, and...

Pancreatogastric Fistula with Fish-Mouth Sign

Hepatobiliary and Pancreatic: an Unusual Cause of Biliary Obstruction

A Common Variant in the CDK8 Gene Is Associated with Sporadic Pituitary Adenoma...

The majority of pituitary adenomas occur in a sporadic context, and in the absence of known genetic predisposition. Three common variants at the NEBL (rs2359536), PCDH15 (rs10763170) and CDK8 (rs17083838) loci were previously associated with sporadic pituitary adenomas in the Han Chinese population, but these findings have not yet been replicated in any other population. The aim of this case-control study was t...

Association of thyroid function, within the euthyroid range, with cardiovascula...

Background: Thyroid hormones are important modulators of cardiovascular function. Both hypothyroidism and hyperthyroidism are known to contribute to an increased cardiovascular risk. It remains uncertain whether thyroid hormones level within the euthyroid range are associated with cardiometabolic risk. We aimed to evaluate the association between thyroid function levels within the euthyroid range and cardiovasc...