The leakage of 5-fluorouracil (5-FU) from elastomeric infusion pumps used in cancer therapy poses a potential risk of unintentional exposure to multiple individuals, including patients’ relatives and healthcare professionals, and may also compromise the accurate administration of 5-FU dosages to patients. This study aimed to develop, validate, and apply an analytical method to detect and quantify 5-FU residues ...
Healthcare professionals face occupational hazardous when handling cytotoxic drugs used for cancer treatment. The International Society of Oncology Pharmacy Practice (ISOPP) standards are the guidelines recommended by the European Parliament for safety procedures but, unlike others (e.g. Occupational Safety and Health Administration (OSHA)), fail to mention the need to use dressings at luer-lock connections to ...
A quercetina é o flavonoide mais utilizado no tratamento de várias doenças, exibindo propriedades antioxidantes, anti-inflamatórias, cardiovasculares, anticancerígenas e de proteção gástrica (Grande et al., 2016). A quercetina pode ser encontrada em várias frutas, vegetais e plantas, e a validação de métodos analíticos para quantificar a quercetina nas mais variadas matrizes é crucial (Singh et al., 2021).
To develop and validate a method for long-term (24-h) objective quantification of absence seizures in the EEG of patients with childhood absence epilepsy (CAE) in their real home environment using a wearable device (waEEG), comparing automatic detection methods with auditory recognition after seizure sonification. The waEEG recording was acquired with two scalp electrodes. Automatic analysis was performed using...
Despite patient ́s benefits, healthcare professionals face occupational hazardous when handling cytotoxic drugs used for cancer treatment. Several organizations outline procedures, conditions, and equipment recommended for safe handling. The International Society of Oncology Pharmacy Practice (ISOPP) standards are the guidelines recommended by the European Parliament but, unlike others (e.g. Occupational Safety...
Pese embora os benefícios potenciais da administração infusional de 5-fluorouracilo (5-FU) em regime de domicílio, já existiram relatos de derrames e resíduos de 5-FU no exterior de bombas infusoras, que reforça a necessidade do desenvolvimento e aplicação de metodologia analítica que permita a sua deteção e quantificação (Chefchaouni et al., 2023).
Objective: To develop and validate a method for long- term (24- h) objective quantification of absence seizures in the EEG of patients with childhood absence epilepsy (CAE) in their real home environment using a wearable device (waEEG), comparing automatic detection methods with auditory recognition after seizure sonification. Methods: The waEEG recording was acquired with two scalp electrodes. Automatic analys...
Background: Despite patient´s benefits, healthcare professionals face occupational hazardous when handling cytotoxic drugs used for cancer treatment [1]. Several organizations outline procedures, conditions, and equipment recommended for safe handling. The International Society of Oncology Pharmacy Practice (ISOPP) standards [2] are the guidelines recommended by the European Parliament but, unlike others (e.g. ...
Bird attacks on crops represent one of the main challenges faced by farmers to make a farm profitable and sustainable. This challenge requires a paradigm shift from old, traditional, ineffective methods, towards the incorporation of smart farming technologies. Intelligent or precision agriculture contributes to the effective and efficient management of resources and, consequently, an increase in production. Thi...
Introdução: O 5-FU é um fármaco citotóxico utilizado no tratamento de vários tipos de cancro, nomeadamente, cancro da cabeça, cancro da mama e cancro do trato gastrointestinal [1]. Em Portugal, o 5-FU é o fármaco mais habitualmente administrado por via intravenosa contínua fora das instalações hospitalares através de bombas infusoras. No seguimento de alguns relatos publicados em literatura cinzenta sobre a e...