5 documents found, page 1 of 1
Phenolic extraction of Moringa oleifera leaves in DES: characterization of the ...
Braham, Fazia; Amaral, Luísa M. P. F.; Biernacki, Krzysztof; Carvalho, Daniel O.; Guido, Luis F.; Magalhães, Júlia M. C. S.; Zaidi, FaridIn this work, a qualitative study of the phenolic content of <i>Moringa oleifera</i> leaves (MO), extracted with deep eutectic solvents (DES) based on choline chloride (ChCl) with lactic acid (LA) or glycerol (GLY), was performed by high-resolution mass spectrometry (HPLC-DAD-ESI-MS<sup>n</sup>). The two solvents (DES-LA and DES-GLY) extract similar classes of phenolics, and ten compounds were identified. The a...
Antiangiogenic and antioxidant in vitro properties of hydroethanolic extract fr...
Costa, Raquel; Azevedo, Daniela; Barata, Pedro; Soares, Raquel; Guido, Luís F.; Carvalho, Daniel O.The Euterpe oleracea fruit (açaí) is a promising source of polyphenols with health-promoting properties. To our knowledge, few studies have focused on the influence of açaí phytochemicals on angiogenesis, with a significant impact on cancer. This study aimed at investigating the phytochemical profile of a purple açaí hydroethanolic extract (AHE) obtained from a commercial dietary powder supplement by high-perfo...
Brewer’s spent grains protects against oxidative DNA damage in Saccharomyces ce...
Moreira, Manuela M.; Carvalho, Daniel O.; Oliveira, Rui Pedro Soares de; Johansson, Björn; Guido, Luís F.Brewer’s spent grain (BSG), obtained from barley malt during brewing, contains high amounts of phenolic acids, predominantly ferulic and p-coumaric acids. The protective effects of BSG extracts against oxidative DNA damage induced by H2O2 in Saccharomyces cerevisiae cells were investigated using an optimized yeast comet assay and flow cytometry. The results indicated that BSG extracts from black malt exhibited ...
Dose-dependent protective and inductive effects of xanthohumol on oxidative DNA...
Carvalho, Daniel O.; Oliveira, Rui Pedro Soares de; Johansson, Björn; Guido, Luís F.The effect of xanthohumol, a prenylflavonoid isolated from the hop plant (Humulus lupulus L.), on Saccharomyces cerevisiae DNA oxidative damage and viability was evaluated. Yeast cultures under oxidative stress, induced by H2O2, displayed stronger growth in the presence of 5 mg/L of xanthohumol than cultures with only H2O2. Likewise, DNA damage assessed by the comet assay was significantly lower in cells co-inc...
Brewer's spent grain from different types of malt: Evaluation of the antioxidan...
Moreira, Manuela M.; Morais, Simone; Carvalho, Daniel O.; Barros, Aquiles A.; Delerue-Matos, Cristina; Guido, Luís F.The antioxidant activity and phenolic composition of brewer's spent grain (BSG) extracts obtained by microwave-assisted extraction from twomalt types (light and darkmalts) were investigated. The total phenolic content (TPC) and antioxidant activity among the light BSG extracts (pilsen, melano, melano 80 and carared)were significantly different (p b 0.05) compared to dark extracts (chocolate and black types), wi...