2 documents found, page 1 of 1
Synthesis, activity and docking studies of eugenol-based glucosides as new agen...
Santos, Marcelo Henrique dos; Hipólito, Taciane Maíra Magalhães; Bastos, Guilherme Tadeu Lemos; Barbosa, Thúlio Wliandon LemosSeventeen new synthetic derivatives of eugenol (6, 8–15 and 8′‐15′) were planned following literature reports on antifungal activities of nitroeugenol and eugenol glucoside. The anti‐Candida activity of these compounds was investigated by in vitro assay and the cytotoxicity evaluation was performed with the most active compounds. The peracetylated glucosides presented better biological results than their hydrox...
Síntese de amidas e sulfonamidas de d-galactopiranosilamina e lactosilamina e a...
Butera, Anna Paola; Souza Filho, José Dias de; Carvalho, Diogo Teixeira; Figueiredo, Rute Cunha; Faria, Luiz Carlos Alves deWe report herein the synthesis of some -D-galactopyranosylamine and -lactosylamine amides and sulfonamides. The interactions of these compounds with lectins from the seeds of Erythrina cristagalli (LEC) and Ricinus communis (RCA120) were evaluated in a hemagglutination inhibitory activity assay. D-Galactose and lactose were used as reference compounds. The -lactosylamine amides and sulfonamides were nearly a...