12 documents found, page 1 of 2

Effect of plasticizer content on the processability of paroxetine-loaded filame...

Poster presented at the 14th PBP World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology. Viena, Austria, 18-21 March 2024

Estudo de caso: otimização do fabrico de medicamentos impressos na Farmácia Com...

Poster apresentado no Congresso Nacional dos Farmacêuticos 2024. Lisboa, 21-23 Novembro 2024

Selection of hydroxypropylcellulose grade for paroxetine 3D printable formulati...

Impact of formulation of drug containing blends on 3D printing by fused deposit...

Preparation of medicines by three dimensional printing and personalization of t...

Estudo de caso : otimização do fabrico de medicamentos impressos na farmácia co...

Exploring environmental settings to improve the printability of paroxetine-load...

The successful integration of hot-melt extrusion (HME) and fused deposition modelling (FDM) depends on a better understanding of the impact of environmental conditions on the printability of formulations, since they significantly affect the properties of the raw materials, whose control is crucial to enable three-dimensional printing (3DP). Hence, the objective of this work was to investigate the correlation be...

Performance and paroxetine stability in tablets manufactured by fused depositio...

Objectives: The objective of this study was to develop a method for the preparation and characterization of paroxetine (PRX) tablets, obtained by coupling hot-melt extrusion and fused deposition modelling (FDM)-based three-dimensional printing (3DP) technology. The impact of the printing process parameters on the drug stability and on the tablets performance was assessed.

Performance and paroxetine stability in tablets manufactured by fused depositio...

"Objectives: The objective of this study was to develop a method for the preparation and characterization of paroxetine (PRX) tablets, obtained by coupling hot-melt extrusion and fused deposition modelling (FDM)-based three-dimensional printing (3DP) technology. The impact of the printing process parameters on the drug stability and on the tablets performance was assessed.

Tuning of paroxetine 3D-printable formulations for fused deposition modelling

This work reports the preliminary development of paroxetine-containing formulations amenable to hot-melt extrusion coupled to fused deposition modelling-based 3D printing. Polymeric matrices were used alone, or added with processing enhancers (e.g., plasticizer and filler). The polymeric formulation containing paroxetine (30% w/w), hydroxypropylcellulose (54% w/w) and excipients (16% w/w of dicalcium dihydrate ...