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Impact of Positive Surgical Margins After Partial Nephrectomy

Carvalho, João André Mendes; Nunes, Pedro; Silva, Edgar Tavares da; Parada, Belmiro; Jarimba, Roberto; Moreira, Pedro; Retroz, Edson; Caetano, Rui

Background: The impact of positive surgical margins (PSMs) after partial nephrectomy (PN) is controversial. Objective: To evaluate the risk factors for a PSM and its impact on overall survival. Design, setting, and participants: This is a retrospective study of 388 patients were submitted to PN between November 2005 and December 2016 in a single centre. Two groups were created: PSM and negative surgical margin ...

Date: 2020   |   Origin: Estudo Geral - Universidade de Coimbra
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Epigenetics: a new therapeutic approach in chronic lymphocytic leukemia

Carvalho, João André Mendes; Carvalho, Filipa; Ribeiro, André; Alves, Vera; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela

Trabalho final do 6º ano médico com vista à atribuição do grau de mestre no âmbito do ciclo de estudos de Mestrado Integrado em Medicina.; Introdução/Objetivos: Atualmente, as alterações epigenéticas têm demonstrado uma possível nova contribuição para o desenvolvimento da Leucemia Linfocítica Crónica B (LLC-B), nomeadamente as desacetilases das histonas e as DNA metiltransferases. Este trabalho tem por objetivo...

Date: 2013   |   Origin: Estudo Geral - Universidade de Coimbra
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