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Antiulcer and antiproliferative properties of spent brewer's yeast peptide extr...

The main objective was to study the antiulcer and antiproliferative potential of yeast peptide extract for further incorporation into functional foods. Peptide concentrates were obtained by hydrolysis of spent brewer's yeast proteins followed by a filtration process. In order to prove the possible protection of gastric mucosa, an animal model with ulcerative lesions caused by oral administration of absolute eth...

Anti-proliferative, anti-inflammatory, anti-ulcerogenic and wound healing prope...

In this study, anti-inflammatory, wound healing and anti-ulcerogenic properties of chitosan were evaluated ‘in vivo’ using wistar rats and swiss adult mice and the anti-proliferative activity was tested ‘in vitro’. The tested chitosans displayed no anti-proliferative or anti-inflammatory properties. The cytotoxic activity of chitosan was found to be non-existent towards eight tumoral cell lines and no significa...

Effect of Artemisia annua L. leaves essential oil and ethanol extract on behavi...

Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T18:57:45Z No. of bitstreams: 1 S0102-695X2008000500008.pdf: 268922 bytes, checksum: e897b94af34ee6f0e1c9f25c42eb40b3 (MD5); Made available in DSpace on 2013-08-22T18:57:45Z (GMT). No. of bitstreams: 1 S0102-695X2008000500008.pdf: 268922 bytes, checksum: e897b94af34ee6f0e1c9f25c42eb40b3 (MD5) Previous issue date: 2008-12-01; Made availabl...

Pharmacological characterization of Solanum cernuum Vell.: 31-norcycloartanones...

Cycloeucalenone (1) and 24-oxo-31-norcycloartanone (2) obtained from Solanum cernuum Vell. were assayed to explore their pharmacologic roles. Previous studies showed that (2) has selective activity against lung tumor cell line (NCIH460) which expresses high levels of COX-2, suggesting its role in inflammatory process, and also a link between chronic inflammation and cancer-associated process. Dichloromethane cr...

Anti-inflammatory activity of chitooligosaccharides in vivo

All the reports to date on the anti-inflammatory activity of chitooligosaccharides (COS) are mostly based on in vitro methods. In this work, the anti-inflammatory activity of two COS mixtures is characterized in vivo (using balb/c mice), following the carrageenan-induced paw edema method. This is a widely accepted animal model of acute inflammation to evaluate the anti-inflammatory effect of drugs. Our data sug...

Do gene à função: investigação do papel dos receptores de glutamato na fisiolog...