Introdução: Os profissionais cabeleireiros são expostos diariamente a substâncias nocivas no seu ambiente de trabalho. Estas podem alterar a função pulmonar, principalmente quando os mesmos não fazem uso dos equipamentos de proteção individual. Objetivo: Avaliar se o uso dos produtos químicos utilizados por cabeleireiros altera a função pulmonar em cabeleireiros. Métodos: Trata-se de um estudo transversal, desc...
The identification of the epidemiological profile of an ICU is fundamental in the aid of decision making and in the creation of strategies aiming at the improvement of the quality of the service. Objective: to identify the profile of patients admitted to the Cardiopulmonary Unit. Methodology: this is a retrospective, descriptive character study with cross section, and presents a quantitative approach, carried o...
To characterize the pro tective effects of the triterpenoid mixture alpha, beta-amyrin (AMY, 20 mg/kg, during 15 days) on the reactivity of isolated aorta of high- fat diet (HFD)-induced obese mice. Male Swiss mice were fed with HFD or normal diet (ND) for 15 weeks. Contractions of thoracic aorta in response to KCl or phen- ylephrine (PHE) and relaxation by acetylcholine (ACh) or sodium nitroprusside (SNP) were...
Herbal compounds rich in triterpenes are well known to regulate glucose and lipid metabolism and to have beneficial effects on metabolicdisorders.ThepresentstudyinvestigatedtheantiobesitypropertiesofresinfromProtiumheptaphyllum(RPH)andthe possible mechanisms in mice fed a high-fat diet (HFD) for 15 weeks. Mice treated with RPH showed decreases in body weight, netenergyintake,abdominalfataccumulation,plasmagluco...
Obesity which is characterized by excessive accumulation of body fat mainly due to the increased consumption of high-calorie foods and sedentary lifestyle is associated with various pathological conditions such as cardiovascular disease, diabetes, musculoskeletal disorders and cancer. Pharmacologic options for the treatment of obesity are limited and have many side effects. In Brazil only two drugs are availabl...
The anti-inflammatory effect of physalin E, a seco-steroid isolated from Physalis angulata L. was evaluated on acute and chronic models of dermatitis induced by 12-O-tetradecanoyl-phorbol-13- acetate (TPA) and oxazolone, respectively, in mouse ear. The changes in ear edema/thickness, production of pro-inflammatory cytokines (TNF- a and IFN- g ), myeloperoxidase (MPO) activity, and histological and immunohistoch...
AIM: To investigate the effects of mangiferin on gas - trointestinal transit (GIT) in normal and constipated mice, together with the possible mechanism. METHODS: Intragastrically-administered charcoal mea was used to measure GIT in overnight starved Swiss mice. In the first experiments, mangiferin (3 mg/kg, 10 mg/kg, 30 mg/kg, and 100 mg/kg, po ) or tegaserod (1 mg/kg, ip ) were administered 30 min before the c...
Quercetin is a plant-derived flavonoid widely known by its anti-oxidant and antiinflammatory properties. Acute pancreatitis (AP) is a disease with a high morbidity and mortality and a complex pathophysiology, with variable involvement of regional tissues or organ systems. Despite of extensive investigations into this disease entity, to date there exists no specific medical treatment for AP. In this study, querc...