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The mutational repertoire of uterine sarcomas and carcinosarcomas in a Brazilia...

Costa, Leonardo Tomiatti da; Anjos, Laura Gonzalez dos; Kagohara, Luciane Tsukamoto; Torrezan, Giovana Tardin; Paula, Claudia A. Andrade de

OBJECTIVES: The present study aimed to contribute to the catalog of genetic mutations involved in the carcinogenic processes of uterine sarcomas (USs) and carcinosarcomas (UCSs), which may assist in the accurate diagnosis of, and selection of treatment regimens for, these conditions. METHODS: We performed gene-targeted next-generation sequencing (NGS) of 409 cancer-related genes in 15 US (7 uterine leiomyosarco...

Date: 2021   |   Origin: Oasisbr

Hypothalamic transcriptional expression of the kis-speptin system and sex stero...

Marcondes, Rodrigo Rodrigues; Carvalho, Katia Candido; Giannocco, Gisele [UNIFESP]; Duarte, Daniele Coelho; Garcia, Natalia; Soares-Junior, Jose Maria

Fundação de Amparo Pesquisa do Estado de São Paulo (FAPESP) -Brazil; Master's degree scholarship Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) -Brazil; OBJECTIVES: Polycystic ovary syndrome is a heterogeneous endocrine disorder that affects reproductive-age women. The mechanisms underlying the endocrine heterogeneity and neuroendocrinology of polycystic ovary syndrome are still unclear. I...

Date: 2019   |   Origin: Oasisbr



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