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Potent nonopioid antinociceptive activity of telocinobufagin in models of acute...

Feitosa, Geissy I.M.C.; Carvalho, Isabella F.; Coelho, Edivaldo B.S.; Monteiro, Marla R.B; Medeiros, Rafael L.; Carvalho, Ellaine D.F.

Introduction: In recent decades, several researches have been conducted in search of new analgesics that do not present the side effects of opioids. In this context, animal venoms contain natural painkillers that have been used for the development of new analgesics. Objective: The aims of this study were to evaluate the antinociceptive effects of telocinobufagin (TCB), a bufadienolide isolated from Rhinella jim...

Date: 2019   |   Origin: Oasisbr
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