56 documents found, page 1 of 6

Pleural Solitary Tumors – Long-Term Prognosis Related To Surgery And Clinicopat...

Introduction: Pleural solitary fibrous tumors (SFTs) are indolent mesenchymal neoplasias, generally with good prognosis, for which complete surgical resection is the gold standard. However, local recurrences and distant metastases are reported at variable rates. Risk-assessing criteria and models determining recurrence and metastatic risk have been proposed, and can impact on patient follow-up strategies. Metho...

Antarctic toothfish Dissostichus mawsoni as a bioindicator of trace and rare ea...

The Antarctic toothfish Dissostichus mawsoni is a Southern Ocean long-lived top predator which is regularly captured on an annual fishery operating in the region. By its biological and ecological characteristics, it is a potential bioindicator for the concentrations of trace and rare earth elements in the Antarctic. As these elements are mainly transferred through the diet and a deficiency or excess of these el...

Insights into S. aureus-Induced Bone Deformation in a Mouse Model of Chronic Os...

Osteomyelitis is an infection of the bone that is often difficult to treat and causes a significant healthcare burden. Staphylococcus aureus is the most common pathogen causing osteomyelitis. Osteomyelitis mouse models have been established to gain further insights into the pathogenesis and host response. Here, we use an established S. aureus hematogenous osteomyelitis mouse model to investigate morphological t...

Metabolic mitochondrial alterations prevail in the female rat heart 8 weeks aft...

The consumption of high-caloric diets strongly contributes to the development of non-communicable diseases (NCDs), including cardiovascular disease, the leading cause of mortality worldwide. Exercise (along with diet intervention) is one of the primary non-pharmacological approaches to promote a healthier lifestyle and counteract the rampant prevalence of NCDs. The present study evaluated the effects of exercis...

Evaluating rotation invariant strategies for mitosis detection through YOLO alg...

Cancer diagnosis is of major importance in the field of human medical pathology, wherein a cell division process known as mitosis constitutes a relevant biological pattern analyzed by professional experts, who seek for such occurrence in presence and number through visual observation of microscopic imagery. This is a time-consuming and exhausting task that can benefit from modern artificial intelligence approac...

Mortality due to respiratory infections: an alert study before COVID-19 pandemic

Objective. Respiratory tract infections remain a common problem in clinical practice with high morbidity and mortality worldwide. In Portugal, pneumonia was the third leading death cause in 2018. Due to COVID-19 pandemic, there is a growing concern about the burden of respiratory diseases and preventable risk factors. The present study started before the pandemic and its aim was to determine the occurrence of p...

Nucleolin Overexpression Predicts Patient Prognosis While Providing a Framework...

Notwithstanding the advances in the treatment of lung cancer with immune checkpoint inhibitors, the high percentage of non-responders supports the development of novel anticancer treatments. Herein, the expression of the onco-target nucleolin in patient-derived pulmonary carcinomas was characterized, along with the assessment of its potential as a therapeutic target. The clinical prognostic value of nucleolin f...

As “bexigas negras” e os museus históricos

The Role of Rosmarinic Acid on the Bioproduction of Gold Nanoparticles as Part ...

Breast cancer is a high-burden malignancy for society, whose impact boosts a continuous search for novel diagnostic and therapeutic tools. Among the recent therapeutic approaches, photothermal therapy (PTT), which causes tumor cell death by hyperthermia after being irradiated with a light source, represents a high-potential strategy. Furthermore, the effectiveness of PTT can be improved by combining near infrar...

The Role of Rosmarinic Acid on the Bioproduction of Gold Nanoparticles as Part ...

Breast cancer is a high-burden malignancy for society, whose impact boosts a continuous search for novel diagnostic and therapeutic tools. Among the recent therapeutic approaches, photothermal therapy (PTT), which causes tumor cell death by hyperthermia after being irradiated with a light source, represents a high-potential strategy. Furthermore, the effectiveness of PTT can be improved by combining near infrar...