53 documents found, page 1 of 6

Analysis of the carbon footprint of a textile company for the automotive industry

This study aims to develop a process to calculate the carbon footprint of a company in the textile sector for the automotive industry, thus addressing a research gap identified in this sector. Based on a structured calculation model, the project aspires to innovate by quantifying not only the greenhouse gas emissions at different stages of the company’s operations, including those generated by the consumed elec...

Sex-related differences in ST-segment elevation myocardial infarction: A Portug...

Introduction and objectives Sex differences among patients with acute myocardial infarctions remain a matter of debate. Inequalities in presentation, diagnosis, treatment, and prognosis are frequently observed, contributing to a worse prognosis in women. The aim of this study was to investigate sex-related differences in Portuguese ST-segment elevation myocardial infarction (STEMI) patients. Methods The authors...

P2Y12 Inhibitor Pretreatment in Non-ST-Segment Elevation Acute Coronary Syndrom...

Background/Objectives: Current guidelines do not specifically address the use of P2Y12 inhibitor (P2Y12i) pretreatment in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) who are expected to undergo a late invasive strategy. Nevertheless, such pretreatment may be considered in patients without a high bleeding risk (Class of Recommendation, IIb; Level of Evidence, C). Despite this ambigu...

Sudden cardiac death in athletes: A 20-year analysis in Portugal

Introduction and objectives Sudden cardiac death (SCD) in athletes is a tragic event, with some evidence remaining controversial. The aim of this study was to evaluate cases of SCD in athletes in Portugal within the last 20 years. Methods An advanced Google search using a combination of several keywords and systematic searches on websites of national newspapers/television stations was conducted. Additionally, 5...

Adherence to the Mediterranean diet among U.Porto students: study of associated...

Gellan gum-based bioink for bioprinting of a mechanically mimetic 3D in vitro l...

The liver is vital for the human body's metabolism, making the development of more predictable and reproducible pathophysiological-relevant three-dimensional (3D) liver models crucial for studying the accumulation of xenobiotics and associated liver diseases. In this work, we describe the development of a bioink comprising 0.2% w/v TayaGel® HA (high acyl gellan gum) and 1.2% w/v Gelzan™ CM (low acyl gellan gum)...

Palácio da Imaginação: práticas de cocriação

O Palácio da Imaginação foi um projeto de investigação-ação, financiado pelo Programa Bairros Saudáveis, implementado no Bairro da Emboladoura, Gondar, Guimarães, e desenvolvido em cocriação com a comunidade.

In vitro and in silico evaluation of psilocybin and psilocin’s interaction with...

Background: Psilocybin is a hallucinogen produced by “magic mushrooms”, being rapidly metabolized in the organism into psilocin [1, 2]. A scientific gap exists regarding the possible interactions between psilocybin/psilocin and CYP450 enzymes. Given their biological importance, and since the binding of drugs to CYP450 enzymes can interfere with the metabolism of other substrates leading to drug-drug interaction...

In vitro and in silico evaluation of 5-MeO-DMT, LSD, and mescaline’s interactio...

Background: 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT), lysergic acid diethylamide (LSD), and mescaline are classic hallucinogens known for their recreational use, which increased in the last decades. Despite some available data on the metabolism of these drugs [1-3], a scientific gap exists regarding their possible interactions with CYP450 enzymes. Nevertheless, this information is of crucial relevance to pr...

In vitro and in silico evaluation of 5-MeO-DMT, LSD, and mescaline’s interactio...

5-Methoxy-N,N-dimethyltryptamine(5-MeO-DMT), lysergic acid diethylamide (LSD), and mescaline are classic hallucinogens known for their recreational use, which increased in the last dec-ades. Despite some available data on the metabolism of these drugs [1-3], a scientific gap exists regarding their possible interactions with CYP450 enzymes. Nevertheless, this information is of crucial relevance to predict drug-d...