24 documents found, page 1 of 3

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In vitro colonic fermentation of clean label ham formulations: gut microbiota m...

Carvalho, Teresa Bento de; Barbosa, Joana Bastos; Carvalho, Nelson Mota de; Komora, Norton; Carvalho, Fátima; Madureira, Ana Raquel; Teixeira, Paula

Consumer wishes for “clean label” products have prompted the rise of these products available in the market. With dietary choices directly influencing market trends, developing novel meat products with natural nitrate and nitrite alternatives is a sought-after premise. Cured meats like ham have been under scrutiny due to their potential harm to human health, having sodium nitrite been theorised to trigger dysbi...


Encapsulation of Akkermansia muciniphila in calcium-alginate matrix: a live bio...

Machado, Daniela; Vedor, Rita; Fonseca, Mariana; Sousa, Sérgio; Barbosa, Joana Cristina; Carvalho, Nelson Mota de; Costa, Célia Maria

Objective: Akkermansia muciniphila is a next-generation probiotic recognized for improving gut barrier function and metabolic health. However, ensuring its viability during processing, storage, and gastrointestinal transit remains a challenge. This study investigated calcium-alginate encapsulation as a strategy for enhancing the stability of A. muciniphila during refrigerated aerobic storage and gastrointestina...


Modulatory effects in microbiota metabolic function triggered by calcium-algina...

Machado, Daniela; Vedor, Rita; Barbosa, Joana Cristina; Carvalho, Nelson Mota de; Costa, Célia Maria; Madureira, Ana Raquel; Gomes, Ana Maria

Probiotics are live microorganisms, that when consumed in suitable amounts, confer a health benefit on the host (Hill et al., 2014). Specifically, they may exert a positive effect on improving intestinal homeostasis by modulating both the microbiota profile and metabolic functions. This modulation may conduct to beneficial alterations in the production of specific organic acids and the consumption of extracellu...


A critical review on in vitro and ex vivo models of the intestinal epithelium o...

Costa, Célia Maria; Carvalho, Nelson Mota de; Oliveira, Diana Luazi de; Madureira, Ana Raquel

Recently, the bioactive potential of several functional ingredients and biomolecules has been evaluated regarding human and animal nutrition. The digestive process from food intake to absorption and metabolism are important events that induce changes in ingredients, which affect their bioactivity. Consequently, there is a need to assess the bioavailability and bioaccessibility of these compounds. The methodolog...


Impact of novel clean label ham formulations on the human gut microbiota

Carvalho, Teresa Bento de; Barbosa, Joana Bastos; Carvalho, Nelson Mota de; Souza, Carla; Costa, Célia; Komora, Norton; Azevedo, Alexandra

Introduction: The influence of diet on the human gut microbiota has been the subject of much debate, particularly in relation to innovative products that are still considered novel. Dietary habits have a fundamental impact on the human gut microbiota, which explains the variations observed between individuals and over the course of a lifetime. The aim of this study was to evaluate the effect of four clean label...


In vivo study of the effect of sugarcane bagasse lignin supplementation on broi...

Carvalho, Nelson Mota de; Souza, Carla Giselly de; Costa, Célia Maria; Castro, Cláudia; Fangueiro, Joana F.; Horta, Bruno; Outor-Monteiro, Divanildo

Since the global restrictions on antibiotics in poultry systems, there has been a growing demand for natural and sustainable feed additives for disease prevention and poultry nutrition. This study evaluated the effects of incorporating sugarcane bagasse (SCB) lignin into broiler chicken diets. The performance of the chickens, including body weight, feed intake, and mortality, as well as intestinal histomorphome...


Production of sustainable postbiotics from sugarcane straw for potential food a...

Oliveira, Ana L. S.; Seara, Marta; Carvalho, Maria João; Carvalho, Nelson Mota de; Costa, Eduardo M.; Silva, Sara; Duarte, Marco; Pintado, Manuela

The production of postbiotics for food applications has been growing in recent years owing to their biological potential and superior technological performance over probiotics. Their production involves the use of synthetic culture media, and in this work, we propose using sugarcane straw as a source of sugar and biological components and a sustainable alternative. Thus, this by-product was used as a substrate ...


Strategies to assess the impact of sustainable functional food ingredients on g...

Carvalho, Nelson Mota de; Oliveira, Diana Luazi; Costa, Célia Maria; Pintado, Maria Estevez; Madureira, Ana Raquel

Nowadays, it is evident that food ingredients have different roles and distinct health benefits to the consumer. Over the past years, the interest in functional foods, especially those targeting gut health, has grown significantly. The use of industrial byproducts as a source of new functional and sustainable ingredients as a response to such demands has raised interest. However, the properties of these ingredi...


Development of a chicken gastrointestinal tract (GIT) simulation model: impact ...

Carvalho, Nelson Mota de; Costa, Célia Maria; Castro, Cláudia; Saleh, Mayra Anton Dib; Pintado, Manuela Estevez; Oliveira, Diana Luazi

A chicken gastrointestinal tract (GIT) simulation model was developed to help predict the potential effects of feed additives supplementation on chicken’ microbiota. The chemical and enzymatic conditions for oral, gastric, intestinal, and cecum fermentation phases were designed to closely resemble the chicken GIT conditions. For cecum fermentation, the inoculum was obtained from the cecal contents of 18 38-day ...


Lignin from sugarcane bagasse as a prebiotic additive for poultry feed

Fangueiro, Joana F.; Carvalho, Nelson Mota de; Antunes, Filipa; Mota, Inês F.; Pintado, Manuela Estevez; Madureira, Ana Raquel; Costa, Patrícia Santos

Diet is a crucial factor on health and well-being of livestock animals. Nutritional strengthening with diet formulations is essential to the livestock industry and animal perfor-mance. Searching for valuable feed additives among by-products may promote not only circular economy, but also functional diets. Lignin from sugarcane bagasse was proposed as a potential prebiotic additive for chickens and incorporated ...


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