163 documents found, page 1 of 17
Sociodemographic and lifestyle factor associated with Mediterranean Dietary Pat...
Trinca, C.; Peres, M.; Santos, N.; Carvalho, S.; Gonçalves, S.; Teixeira, B.; Poínhos, Rui; Oliveira, B.M.P.M.; Afonso, Cláudia
Unleashing the antibiofouling potential of nano-structured ZrN-Cu coating throu...
Castro, José D.; Carvalho, Isabel; Sánchez-López, J. C.; Rojas, T. C.; Escobar-Galindo, R.; Carvalho, S.The world needs more environmentally friendly materials every time, especially when the application demands constant interaction with fragile habitats. The naval industry is a crucial player in a globalised economy, and the ambient impact of ships on the seas is well-known. Biofouling is one of the significant issues in this industry, and paints with biocides are used as the principal coating solution. However,...
Antimicrobial polymeric surfaces using embedded silver nanoparticles
Sharma, Pooja; Fialho, Luisa; Figueiredo, Nuno Miguel; Serra, Ricardo; Cavaleiro, Albano; Carvalho, S.Pathogens (disease-causing microorganisms) can survive up to a few days on surfaces and can propagate through surfaces in high percentages, and thus, these surfaces turn into a primary source of pathogen transmission. To prevent and mitigate pathogen transmission, antimicrobial surfaces seem to be a promising option that can be prepared by using resilient, mass-produced polymers with partly embedded antimicrobi...
Deep learning approach to the texture optimization problem for friction control...
Silva, Alexandre Daniel Mendonça Faria; Lenzi, Veniero; Pyrlin, Sergey; Carvalho, S.; Cavaleiro, Albano; Marques, L.The possibility to control friction through surface microtexturing can offer invaluable advantages in many fields, from wear and pollution reduction in the transportation industry to improved adhesion and grip. Unfortunately, the texture optimization problem is very hard to solve using traditional experimental and numerical methods, due to the complexity of the texture configuration space. Here, we apply machin...
The disease modelling value of a folklore FAIRYtale: SHEDing light over a speci...
Carvalho, S.; Santos, J.I.; Moreira, L.; Gaspar, P.; Gonçalves, M.; Encarnação, M.; Ribeiro, D.; Duarte, A.; Prata, M.J.; Coutinho, M.F.The problem we are addressing: Despite extensive research, the links between accumulation of glycosaminoglycans (GAGs) and the clinical features seen in patients suffering from various forms of Mucopolysaccharidoses (MPSs) have yet to be further elucidated. These Lysosomal Storage Diseases (LSDs) present symptoms, which may (or may not) include critical musculoskeletal and cardiovascular alterations, respirator...
Nonlinear systems of parabolic IBVP: A stable super-supraconvergent fully discr...
Carvalho, S.; Ferreira, J. A.; Pena, G.The main purpose of this paper is the design of discretizations for second order nonlinear parabolic initial boundary value problems which are stable and present second order of convergence with respect to H1-discrete norms. The convergence results are established assuming that the solutions are in H3. The stability analysis of numerical methods around a numerical solution requires the uniform boundness of such...
Spectroscopic detection of pigments in tissues: correlation with tissue aging a...
Oliveira, Luís M.; Goncalves, T. M.; Botelho, A. R.; Martins, I. S.; Silva, H. F.; Carneiro, I.; Carvalho, S.; Henrique, R.; Tuchin, V. V.The direct calculation of the absorption coefficient spectra of various tissues from spectral measurements allowed to retrieve the contents of melanin and lipofuscin. In the rabbit brain cortex, 1.8 times higher melanin content is explained by the neuron degeneration process. Similar melanin and lipofuscin contents were found in the rabbit pancreas as a result of the tissue aging process. The conversion of 83 %...
Role of genetic polymorphisms on neuroplasticity pathways in a cohort of Portug...
Santos, M.; Carvalho, S.; Lima, L.; Mota-Pereira, J.; Pimentel, P.; Correia, D.; Maia, D.; Gomes, S.; Cruz, A.; Medeiros, R.Growing evidence suggests the implication of brain plasticity in antidepressant drug (AD) efficacy. Several authors have been pointing out the role of the BDNF-TrkB signaling pathway, including the downstream kinases Akt and ERK, and the mTOR pathway in neuroplasticity [1-3]. Furthermore, the prediction of AD response phenotypes of depressed patients treated with AD drugs remains a challenge for clinicians. Alt...
Comparative study of titanium alloys machinability used for medical applications
Festas, A. J.; Carvalho, S.; Horovistiz, A.; Ramos, A.; Davim, J. P.CNC machining manufacturing is critical to the development of biomedical industries, especially orthopaedic implants. Understanding a material's machinability under different cutting conditions is essential for component design as well as for optimizing the machining process. Despite their widespread use in the biomedical industry, α+β-type titanium (Ti) alloys, such as Ti-6Al-4V and Ti-6Al-7Nb, are being repla...
Zn-Fe flower-like nanoparticles growth by gas condensation
Lamsaf, H.; Lenzi, V.; Marques, L.; Rebouta, L.; Carvalho, S.; Ballesteros, Lina F.; Cerqueira, Miguel Ângelo Parente Ribeiro; Teixeira, J. A.Bimetallic nanoparticles have gained attention in the last decade due to their unusual characteristics compared to monometallic counterparts. However, production of such particles with controlled morphologies and composition need to be explored and the mechanisms understood. In this work, we demonstrate a fast and simple process to obtain flower-like Zn-Fe (Zinc-Iron) nanoparticles (NPs) using a hybrid system b...