164 documents found, page 1 of 17
Self-efficacy and attachment styles mediate the impact of early life trauma on ...
Coelho, Catarina Gomes; Cerri, Luiza; Leite, Leite; Machado, Paulo P. P.; Carvalho, SandraWhile early life trauma (ELT) is known to contribute to poor physical and psychological health in adulthood, not all individuals exposed to ELT develop mental illness. This suggests the presence of potential mediating factors that influence this relationship. This study examines the mediating effects of self-efficacy and attachment styles on the relationship between ELT and negative emotional states (NEs) in a ...
Quality of life in hospitalized COVID-19 patients: The role of psychosocial, in...
Pereira, M. Graça; Vilaça, Margarida; Santos, Martim; Carvalho, Sandra; Leite, Jorge; Santos Silva, André; Consentino, Marco; Marino, FrancaIntroduction: A significant proportion of COVID-19 survivors continues to suffer from persistent physical and psychological sequelae after hospital discharge. Materials and methods: This cross-sectional study aimed to analyze the roles of psychosocial, inflammatory, and dopaminergic pathways in the relationship between posttraumatic stress symptoms (PTSS), rumination, and quality of life (QoL) in patients hospi...
Delayed effects of tDCS combined with cognitive behavioral therapy in major dep...
Carvalho, Sandra; Gomes Coelho, Catarina; Leite, JorgeAims: This pilot study assessed the potential psychosocial and therapeutic impacts of augmenting transcranial direct current stimulation (tDCS) with cognitive behavioral therapy (CBT) in treatment-naïve patients diagnosed with major depressive disorder (MDD). Methods: In this double-blind randomized controlled trial, 10 subjects were randomized into two groups—CBT with active tDCS (active tDCS; n = 6; M = 33.3 ...
Beyond COVID-19 infection: cognitive and emotional pathways between posttraumat...
Vilaça, Margarida; Carvalho, Sandra; Leite, Jorge; Leite, Fernanda; Pereira, M. GraçaBackground: Hospitalization during the COVID-19 pandemic has been linked with increased psychological distress, cognitive impairment, and reduced quality of life (QoL). Posttraumatic stress symptoms (PTSS) and rumination may significantly influence QoL outcomes, yet the mechanisms underlying these effects remain poorly understood. Based on the Cognitive Aging Model, this study examines the mediating effects of ...
Report Approval for Transcranial Electrical Stimulation (RATES): expert recomme...
Nejati, Vahid; Vaziri, Zahra; Antal, Andrea; Antonenko, Daria; Behroozmand, Roozbeh; Bestmann, Sven; Brunelin, Jerome; Brunoni, Andre R.Transcranial electrical stimulation (tES) has gained substantial momentum as a research and therapeutic tool; however, it suffers from challenges related to reproducibility and quality assessment due to the absence of standardized reporting practices. Here we aim to develop a comprehensive and consensus-based checklist for conducting and reporting tES studies to enhance the quality of research and reports. In t...
MAGNITUDE: transcranial magnetic stimulation for treatment-resistant Obsessive-...
Rech, Lavinia; Vivanco, Ricardo A.; Guersoni, Ana Claudia; Ninapaytan, Gianina M. Crisóstmono; Rivera, Paulina Bonilla; Ramos-Orosco, Elisabeth J.Obsessive–Compulsive Disorder (OCD) is a chronic psychiatric condition with a lifetime prevalence of 2–3%. It significantly burdens quality of life and is associated with substantial economic and disease burdens. Cognitive-behavioral therapy and high-dose selective serotonin reuptake inhibitors are considered the first-line treatments for OCD. Approximately two-thirds of patients with Obsessive–Compulsive Disor...
Multifunctional alumina scaffolds with enhanced bioactivity and antimicrobial p...
Santo, Daniela; Rodarte, Mikhael; Andreto, Crislayne; Cavaleiro, Diogo; Carvalho, Isabel; Balestra, Roseli; Carvalho, SandraInert ceramic implants suffer from significant complications such as lack of osseointegration, biofilm formation, and infections, necessitating the development of novel materials with both osteogenic and antibacterial properties to prevent implant failure. In this study, we aimed to multifunctionalize a tridimensional macroporous alumina scaffold with a biomimetic calcium phosphate (CaP) coating combined with a...
Customisation of PVD coatings for biomedical devices
Santo, Daniela; Castro, José D.; Cruz, Sandra; Carvalho, Isabel; Cavaleiro, Albano; Carvalho, SandraIn recent years, physical vapor deposition (PVD) has emerged as a powerful technique for surface modification, offering a wide range of possibilities to improve the properties of medical devices. This review explores the fundamentals and versatility of PVD coatings in biomedical applications, highlighting their potential to revolutionise the field. Biocompatibility is crucial in successfully integrating medical...
Personalized language training and bi-hemispheric tDCS improve language connect...
Carvalho, Sandra; Mendes, Augusto J.; Pinto, José Miguel Soares Pereira; Sampaio, Adriana; Leite, JorgeBackground: Transcranial direct current stimulation (tDCS) has emerged as a promising neuromodulatory tool for language rehabilitation in chronic aphasia. However, the effects of bi-hemispheric, multisite stimulation remain largely unexplored, especially in people with chronic and treatment-resistant language impairments. The goal of this study is to look at the effects on behavior and brain activity of an indi...
Transcranial Direct Current Stimulation decreases P3 amplitude and inherent del...
Mendes, Augusto J.; Galdo-Álvarez, Santiago; Lema, Alberto; Carvalho, Sandra; Leite, JorgeThe inability to wait for a target before initiating an action (i.e., waiting impulsivity) is one of the main features of addictive behaviors. Current interventions for addiction, such as transcranial Direct Current Stimulation (tDCS), have been suggested to improve this inability. Nonetheless, the effects of tDCS on waiting impulsivity and underlying electrophysiological (EEG) markers are still not clear. Ther...