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Self-efficacy and attachment styles mediate the impact of early life trauma on ...

Coelho, Catarina Gomes; Cerri, Luiza; Leite, Leite; Machado, Paulo P. P.; Carvalho, Sandra

While early life trauma (ELT) is known to contribute to poor physical and psychological health in adulthood, not all individuals exposed to ELT develop mental illness. This suggests the presence of potential mediating factors that influence this relationship. This study examines the mediating effects of self-efficacy and attachment styles on the relationship between ELT and negative emotional states (NEs) in a ...


Quality of life in hospitalized COVID-19 patients: The role of psychosocial, in...

Pereira, M. Graça; Vilaça, Margarida; Santos, Martim; Carvalho, Sandra; Leite, Jorge; Santos Silva, André; Consentino, Marco; Marino, Franca

Introduction: A significant proportion of COVID-19 survivors continues to suffer from persistent physical and psychological sequelae after hospital discharge. Materials and methods: This cross-sectional study aimed to analyze the roles of psychosocial, inflammatory, and dopaminergic pathways in the relationship between posttraumatic stress symptoms (PTSS), rumination, and quality of life (QoL) in patients hospi...


The emotional movie database (EMDB): an expanded toolkit for emotion research

Carvalho, Sandra; Coelho, Catarina Gomes; Mendes, Augusto J.; Gonçalves, Óscar F.; Leite, Jorge

Emotion-eliciting film clips are widely used in psychological, neuroscientific, and affective computing research as stan-dardized stimuli for the study of emotional responses. The Emotional Movie Database (EMDB) was originally developedto provide silent film clips for emotion research; however, limitations in stimulus diversity motivated its expansion. Thepresent study extends the EMDB by introducing four addit...


When asymmetry becomes “giant”: A Rare Case of Juvenile Fibroadenoma

Miranda, Carlota; Ferreira, Mónica; Carvalho, Sandra; Sampaio, Clara; Nunes, Susana; Morujão, Inês; Morgado, Carolina; Vitorino, Carlos

Juvenile fibroadenoma account for approximately 4% of all fibroadenomas, and giant juvenile fibroadenomas are extremely rare, with an incidence of 0.5%. Fibroadenomas can reach large sizes, and surgical intervention poses an aesthetic challenge, particularly in developing breasts. We report the case of a 13-year-old girl who presented with rapid enlargement of the left breast. Physical examination revealed a lo...

Date: 2026   |   Origin: Revista Portuguesa de Cirurgia

Executive dysfunction as a transdiagnostic mechanism of psychopathology: a neur...

Carvalho, Sandra

Psychiatric disorders are typically classified using categorical diagnostic systems based on symptom clusters. However, these frameworks often fail to capture the cognitive and neurobiological mechanisms that transcend diagnostic boundaries and influence everyday functioning. Executive dysfunction, encompassing impairments in inhibitory control, working memory, cognitive flexibility, planning, and emotion regul...


Delayed effects of tDCS combined with cognitive behavioral therapy in major dep...

Carvalho, Sandra; Gomes Coelho, Catarina; Leite, Jorge

Aims: This pilot study assessed the potential psychosocial and therapeutic impacts of augmenting transcranial direct current stimulation (tDCS) with cognitive behavioral therapy (CBT) in treatment-naïve patients diagnosed with major depressive disorder (MDD). Methods: In this double-blind randomized controlled trial, 10 subjects were randomized into two groups—CBT with active tDCS (active tDCS; n = 6; M = 33.3 ...


Beyond COVID-19 infection: cognitive and emotional pathways between posttraumat...

Vilaça, Margarida; Carvalho, Sandra; Leite, Jorge; Leite, Fernanda; Pereira, M. Graça

Background: Hospitalization during the COVID-19 pandemic has been linked with increased psychological distress, cognitive impairment, and reduced quality of life (QoL). Posttraumatic stress symptoms (PTSS) and rumination may significantly influence QoL outcomes, yet the mechanisms underlying these effects remain poorly understood. Based on the Cognitive Aging Model, this study examines the mediating effects of ...


Report Approval for Transcranial Electrical Stimulation (RATES): expert recomme...

Nejati, Vahid; Vaziri, Zahra; Antal, Andrea; Antonenko, Daria; Behroozmand, Roozbeh; Bestmann, Sven; Brunelin, Jerome; Brunoni, Andre R.

Transcranial electrical stimulation (tES) has gained substantial momentum as a research and therapeutic tool; however, it suffers from challenges related to reproducibility and quality assessment due to the absence of standardized reporting practices. Here we aim to develop a comprehensive and consensus-based checklist for conducting and reporting tES studies to enhance the quality of research and reports. In t...


MAGNITUDE: transcranial magnetic stimulation for treatment-resistant Obsessive-...

Rech, Lavinia; Vivanco, Ricardo A.; Guersoni, Ana Claudia; Ninapaytan, Gianina M. Crisóstmono; Rivera, Paulina Bonilla; Ramos-Orosco, Elisabeth J.

Obsessive–Compulsive Disorder (OCD) is a chronic psychiatric condition with a lifetime prevalence of 2–3%. It significantly burdens quality of life and is associated with substantial economic and disease burdens. Cognitive-behavioral therapy and high-dose selective serotonin reuptake inhibitors are considered the first-line treatments for OCD. Approximately two-thirds of patients with Obsessive–Compulsive Disor...


Multifunctional alumina scaffolds with enhanced bioactivity and antimicrobial p...

Santo, Daniela; Rodarte, Mikhael; Andreto, Crislayne; Cavaleiro, Diogo; Carvalho, Isabel; Balestra, Roseli; Carvalho, Sandra

Inert ceramic implants suffer from significant complications such as lack of osseointegration, biofilm formation, and infections, necessitating the development of novel materials with both osteogenic and antibacterial properties to prevent implant failure. In this study, we aimed to multifunctionalize a tridimensional macroporous alumina scaffold with a biomimetic calcium phosphate (CaP) coating combined with a...


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