13 documents found, page 1 of 2

Gastrointestinal Metastatic Melanoma: The Key for Diagnosis

Spontaneous Bacterial Peritonitis in Cirrhotic Patients: A Shift in the Microbi...

Abstract Introduction: Over the last decade, a shift in the spontaneous bacterial peritonitis (SBP) microbial pattern toward an increasing incidence of gram-positive and multidrug-resistant (MDR) bacteria has been reported. Systematic surveillance of the local microbiological scenario and antibiotic resistance is crucial to SBP treatment success. The main objective of this study was to evaluate the microbiologi...

Fever of Unknown Origin in a Portuguese Tertiary Hospital: A Cohort Study

Abstract lntroduction: Fever of unknown origin (FUO) remains a major diagnostic challenge, despite advances in the medical field. lt can be caused by a broad spectrum of diseases with very different prognostic outcomes. Constant re-evaluation of clínical data is essential considering the dynamic changes in disease patterns. We aim to understand which clínical approach is most commonly used and recognize our loc...

A Case of Liver Injury after Exposure to Isopropanol: A Challenging Diagnosis

Abstract: Drug-induced liver injury is hardly diagnosed, considering not only the wide range of hepatotoxic substances but also the diversity of associated phenotypes and the absence of specific biomarkers. Symptom chronology, drug or toxic exposure, and temporal association help to establish the diagnosis. Exposure to isopropanol has known but rare toxic effects. We report the clinical case of a 33-year-old fe...

Case of Flexural Exanthema as a Presenting Sign for COVID-19

ABSTRACT We report a case of a 84-year-old male hospitalized for bacterial pneumonia who, during hospitalization, developed a flexural exanthema in parallel with a positive swab for SARS-CoV-2. Supportive therapy was instituted, the rash disappeared in 7 days and the patient fully recovered. At the same time, two other cases of SARS-CoV-2 infection occurred in the same ward. Histopathology and immunohistochemis...

A Case of Severe Cholestasis due to Hepatic AL Amyloidosis

Introduction: Immunoglobulin light chain-associated amyloidosis results from extracellular tissue deposition of fibrilforming monoclonal immunoglobulin light chains, secreted by a clone of plasma cells. Although the liver is often involved histologically, most cases are clinically asymptomatic, and severe intrahepatic cholestasis as the primary manifestation of the disease is rare. Clinical Case: We report an u...

Anemia Hemolítica num Serviço de Medicina Interna: Caracterização da População

Introdução:A anemia hemolítica representa 5% de todas as anemias e caracteriza-se por uma redução do tempo de vida dos glóbulos vermelhos (GV). A destruição dos GV pode resultar de fenómenos hemolíticos intravasculares ou extravasculares, sendo os últimos mais frequentemente associados a fenómenos autoimunes, toxicidade a químicos/ fármacos, infeções, hiperesplenismo e destruição mecânica. O objetivo do estudo ...

Internamento em Medicina Interna: Evolução em 20 Anos num Hospital Universitário

Introdução: O internamento nos serviços de Medicina Interna tem sofrido alterações ao longo dos anos, com consequente modificação na tipologia de doentes. O objetivo deste trabalho é avaliar a evolução dos internamentos de Medicina Interna num hospital central, com um intervalo de 20 anos. Material e Métodos: Utilizando registos da base dos Grupos de Diagnósticos Homogéneos, avaliaram-se os internamentos nos se...

Streptococcus bovis Bacteremia: Clinical Correlates in a Retrospective Analysis

Introduction:An association between colorectal neoplasm and Streptococcus bovis bacteremia was first suggested in 1951. Decades later, the extent and nature of this association are still not completely understood. The aim of this study was to review all Streptococcus bovis bacteremic episodes documented at a tertiary-care centre. Material and Methods: Retrospective analysis of patients with Streptococcus bovis ...

Immune thrombocytopenia associated with pleural and pericardial tuberculosis: c...