21 documents found, page 1 of 3
Spilanthol: occurrence, extraction, chemistry and biological activities
Barbosa,Alan F.; Carvalho,Mário G. de; Smith,Robert E.; Sabaa-Srur,Armando U.O.Abstract Spilanthol (C14H23NO, 221.339 g/mol) is a bioactive compound that is found in many different plants that are used as traditional remedies throughout the world. It is present in Heliopsis longipes and several species in the genus Acmella, including A. oleracea L., also known as paracress and jambu. Its leaves and flowers have sensory properties (pungency, tingling, numbing, mouth-watering) that make it ...
Effects of Acmella oleracea methanolic extract and fractions on the tyrosinase ...
Barbosa,Alan F.; Silva,Keila C.B.; Oliveira,Márcia C.C. de; Carvalho,Mário G. de; Srur,Armando U.O. SabaaAbstract The aim of the current study is to evaluate the effect of Acmella oleracea (L.) R.K. Jansen, Asteraceae, methanolic extract, hexane (84.28% spilanthol) and dichloromethane (approximately 100% spilanthol) fractions on the tyrosinase enzyme. The dehydrated jambu extract was obtained through maceration using methanol. The extract residue was solubilized in MeOH/H2O (8:2) and subjected to liq.–liq. partiti...
CONSTITUINTES QUÍMICOS E ATIVIDADE ANTIOXIDANTE IN VIVO DE FLAVONOIDES ISOLADOS...
Ferreira,Rafaela O.; Carvalho Junior,Almir R. de; Riger,Cristiano J.; Castro,Rosane N.; Silva,Tania M. S. da; Carvalho,Mário G. deThe phytochemical investigation of Clusia lanceolata leaves yielded fourteen compounds including six flavones, vitexin, isovitexin, isovitexin-2"-O-α-L-rhamnopyranoside, vitexin-2"-O-α-L-rhamnopyranoside, orientin and isoorientin, two phaeophytins [132-hydroxy-(132-S-)-phaeophytin a and 132-hydroxy-(132-R)-phaeophytin a], two triterpenes, α- and β-amyrin, and four steroids, β-sitosterol, stigmasterol, sitostero...
Distribution of metabolites in galled and non-galled leaves of Clusia lanceolat...
Ferreira,Rafaela O.; Carvalho Junior,Almir R. de; Silva,Telma M.G. da; Castro,Rosane N.; Silva,Tania M.S. da; Carvalho,Mário G. deEssential oils of galled and non-galled leaves of Clusia lanceolataCambess., Clusiaceae, were obtained by hydrodistillation and analyzed by GC and GC/MS. The chemical composition of both oils was similar, with a predominance of sesquiterpene caryophyllenes. The extracts from the leaves were evaluated regarding total phenols, flavonoids and proanthocyanidins. Galled leaves showed higher levels of phenolics and p...
Other compounds isolated from Simira glaziovii and the ¹H and 13C NMR chemical ...
Araújo,Marcelo F. de; Braz-Filho,Raimundo; Carvalho,Mário G. de; Vieira,Ivo J. CurcinoA new triterpene, 1-epi-castanopsol, besides eleven known compounds: sitosterol, stigmasterol, campesterol, lupeol, lupenone, simirane B, syringaresinol, scopoletin, isofraxidin, 6,7,8-trimethoxycoumarin and harman, were isolated from the wood of Simira glaziovii. The structures of the known compounds were defined by 1D, 2D ¹H, 13C NMR spectra data analyses and comparison with literature data. The detailed spec...
Chemical constituents from Piptadenia rigida Benth., Fabaceae, "angico"
Carvalho,Mário G. de; Gomes,Mário S. R.; Oliveira,Márcia C. C. de; Silva,Cleber J. da; Carvalho,Acácio G. deThe phytochemical investigation of the roots of Piptadenia rigida Benth., Fabaceae, known as "angico", afforded sitosterol, lupeol, betuline, the chalcone isoliquiritigenin, the flavonoids, 7,4'-dihydroxyflavone, 7,3',4'-trihydroxyflavone, 7,8,3',4'-tetrahydroxyflavanone, 4-hydroxy-3,5-dimethoxybenzaldehyde and methyl-3,4-dihydroxy-benzoate. Both flavones were also isolated from the branches of this plant. Five...
Chemical constituents of Piptadenia gonoacantha (Mart.) J.F. Macbr (pau jacaré)
Carvalho,Mário G. de; Cardozo,Maritza A.R.; Catunda Junior,Francisco E.A.; Carvalho,Acácio G. deThe phytochemical investigation of Piptadenia gonoacantha (Mart.) J.F. Macbr. (Leguminosae-Mimosoideae), commonly known as "pau jacaré" (alligator stick), afforded sitosterol, campesterol, stigmasterol, the N-benzoylphenylalanine-2-benzoylamide-3-phenylpropyl ester, known as asperphenamate, sitosterol-3-O-β-D-glucopyranoside, besides three flavonoids, apigenin, 5-O-methylapigenin and 7,4'-dihydroxy-3',5-dimetho...
Other chemical constituents isolated from Solanum crinitum Lam. (Solanaceae)
Cornelius,Marli T. F.; Carvalho,Mário G. de; Silva,Tania M. S. da; Alves,Cassia C. F.; Siston,Ana P. N.; Alves,Kelly Z.; Sant'Anna,Carlos M. R.The phytochemical investigation of Solanum crinitum Lam led to the isolation from the fruit trichomes of four flavonoids, tiliroside (1), astragalin (2), kaempferol (3), biochanin A-7-O-β-D-apiofuranosyl-(1→5)-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside (7), along with 4-hydroxybenzoic acid (12), and four cinnamic acid derivatives, cis- and trans- coumaric acids (10 and 11) and cis- and trans- ethyl coumarate (...
New iodine derivatives of flavonol and isoflavone
Carvalho,Mário G. de; Silva,Virginia C. da; Silva,Tânia M.S. da; Camara,Celso A.; Braz-Filho,RaimundoThe reaction of the flavonol 3,7,3', 4'-tetra-O-methylquercetin (1) and of the isoflavone 7,4'-di-O-methylgenistein (2) with alkaline iodine in methanol afforded four new iodine derivatives: 8-iodo-5-hydroxy-3,7,3', 4'-tetramethoxy- flavone (1a) and 6-iodo-5-hydroxy-3,7,3', 4'-tetramethoxyflavone (1b) from 1; 2 afforded a mixture of two compounds, identified as a racemic mixture of (±)-trans-5-hydroxy-2,3,7,4'-...
Outros constituintes isolados de Licania arianeae (Chrysobalanaceae)
Carvalho,Mário G. de; Costa,Patrícia M. daO ácido flavona-6-sulfônico, 4'-O-metil-5,7-diidroxi-flavona-6-sulfonato, conhecido como niruriflavona, e a saponina, ácido 3-O-[6'-O-4-hidroxibenzoil]-²-D-galactopiranosil-ursa-12-en-28-óico, foram isolados, respectivamente, de madeira e folhas de Licania arianeae. As estruturas foram estabelecidas através da análise de espectros de massas e RMN incluindo experimentos bidimensionais.