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Atividade anticolinesterásica e perfil químico de uma fração cromatográfica ati...

Marques,Thiago Henrique Costa; Santos,Pauline Sousa dos; Freitas,Rivelilson Mendes de; Carvalho,Rusbene Bruno Fonseca de; Melo,Cassio Herbert Santos de

This work describes the isolation of an active flavonoid fraction and identification of isorhamnetin 3-O-β-D-(6''-acetyl)-galactopyranoside from flowers of B. perennis, and also the evaluation of anticholinesterase (AChE) activity of ethanolic extract from flowers (EEF) and the active fraction. The chemical structure of the flavonoid was defined on the basis of spectroscopic ¹H NMR, IR and UV data. EEF or flavo...

Date: 2013   |   Origin: Oasisbr

Composição química e atividade anticolinesterásica de uma fração ativa do extra...

Carvalho,Rusbene Bruno Fonseca de; Almeida,Antonia Amanda Cardoso de; Freitas,Rivelilson Mendes de; Lima,Luciano Silva; David,Juceni Pereira

This paper describes the chemical composition and acetylcholinesterase inhibition of an active chromatographic fraction of the EtOAc extract of Citrus limon leaves. The composition of the active fraction presented a mixture of two coumarins, 5,8-dimethoxy-psoralen and 5,7- dimethoxycoumarin, identified by ¹H and ¹³C NMR data analysis, including DEPT, COSY, HMBC and HSQC experiments. It was also demonstrated tha...

Date: 2013   |   Origin: Oasisbr

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